116211-30-4Relevant articles and documents
NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS
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Page/Page column 129, (2020/01/24)
Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R3, and R4 are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGK α) and diacylglycerol kinase zeta (DGKζ ), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.
COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF AS INHIBITORS OF RAN GTPASE
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Paragraph 00201; 00203, (2019/04/09)
Compounds of general formula IA, IB and IC outlined below, including pharmaceutically acceptable salts, solvates and hydrates thereof. Such compounds and pharmaceutical compositions comprising them may be used in medical conditions involving Ran GTPase.
Synthesis and pharmacological properties of 'soft drug' derivatives related to perhexiline
Marciniak,Decolin,Leclerc,Decker,Schwartz
, p. 2289 - 2296 (2007/10/02)
In the hope of reducing the toxicity of perhexiline, a series of 27 cyclohexylaralkylamines II based on the 'soft drug' concept and incorporating an amide function were synthesized. In a preliminary screening, compounds were evaluated for their α-adrenoly
