116227-75-9

Usage

Chemical class

pyrazole

Physical form

yellow to orange powder

Aromatic and azo functional groups

used as a dye and pigment

Building block in pharmaceutical research

used in the synthesis of potential pharmaceutical compounds

Anti-inflammatory and antioxidant properties

studied for its potential therapeutic effects

Corrosion inhibition

potential application in metal processing industry

Upstream product

• 89-25-8 edaravone 
• 106-47-8 4-chloro-aniline 
• 112996-61-9 5-methyl-2-phenyl-2H-pyrazole-3,4-dione-4-(4-chloro-phenylhydrazone) 

Relevant academic research and scientific papers

A Simple Route for the Synthesis of Chlorosubstituted Arylazobenzenes, Arylazonaphtalenes, and Arylazopyrazoles

The reaction of arylazophenoles and arylazohydroxypyrazoles (or their tautomer hydrazones) 10, 11, and 15 with POCl3 in dimethylformamide yields chlorosubstituted arylazobenzenes or arylazopyrazoles 12, 13 and 16, resp., in moderate to high yields.The substitution of the OH-group by the Cl-moiety is favoured by acceptor substituents in the aryl fragments ortho- and/or para-linked to the azo group.In case that arylazocompounds derived from resorcinol are used the substitution reaction runs in a stepwise manner giving raise to the formation of o-hydroxy-p-chlorosubstit uted azo compounds 18 primarily and then of dichlorosubstituted azo compounds 19.