116261-30-4

Basic information

• Product Name: trans-(±)-Dihydro-3,4-bis[[3-Methoxy-4-(phenylMethoxy)phenyl]Methyl]-2(3H)-furanone
• Synonyms: (3R,4R)-rel-Dihydro-3,4-bis[[3-Methoxy-4-(phenylMethoxy)phenyl]Methyl]-2(3H)-furanone;rac Matairesinol Dibenzyl Diether;trans-(±)-Dihydro-3,4-bis[[3-Methoxy-4-(phenylMethoxy)phenyl]Methyl]-2(3H)-furanone
• CAS NO: 116261-30-4
• Molecular Formula: C₃₄H₃₄O₆
• Molecular Weight: 538.63016
• Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 116261-30-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 128 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
• Boiling Point: 701.1±55.0 °C(Predicted)
• Appearance: /
• Density: 1.196±0.06 g/cm3(Predicted)
• Solubility: Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: trans-(±)-Dihydro-3,4-bis[[3-Methoxy-4-(phenylMethoxy)phenyl]Methyl]-2(3H)-furanone(CAS DataBase Reference)
• NIST Chemistry Reference: trans-(±)-Dihydro-3,4-bis[[3-Methoxy-4-(phenylMethoxy)phenyl]Methyl]-2(3H)-furanone(116261-30-4)
• EPA Substance Registry System: trans-(±)-Dihydro-3,4-bis[[3-Methoxy-4-(phenylMethoxy)phenyl]Methyl]-2(3H)-furanone(116261-30-4)

Safety Data

• Hazardous Substances Data: 116261-30-4(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

Different sources of media describe the Uses of 116261-30-4 differently. You can refer to the following data:
1. Protected rac Matairesinol (M197850). A plant lignan found in oil seeds, whole grains, vegetables and fruits that may offer health benefits when used in daily diet. It is a precursor to enterolignans that have potential anticancer properties and may reduce the risk of cardiovascular diseases.
2. rac Matairesinol Dibenzyl Diether is a plant lignan found in oil seeds, whole grains, vegetables and fruits that may offer health benefits when used in daily diet. It is a precursor to enterolignans that have potential anticancer properties and may reduce the risk of cardiovascular diseases.

Upstream product

• 116185-13-8 (3S,4S)-3,4-Bis-(4-benzyloxy-3-methoxy-benzyl)-dihydro-furan-2,5-dione 
• 116185-11-6 benzyl 3-[4-(benzyloxy)-3-methoxyphenyl]propanoate 
• 116185-12-7 2,3-bis<<3-methoxy-4-(phenylmethoxy)phenyl>methyl>-butanedioic acid 
• 30034-49-2 β-(4-benzyloxy-3-methoxyphenyl)propionic acid 
• 1135-23-5 3-(4-hydroxy-3-methoxyphenyl)propionic acid 
• 1135-24-6 (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid 

Downstream Products

• 34444-37-6 wikstromol 
• 34444-37-6 epiwikstromol 
• 33464-73-2 3,4-bis<(3,4-dimethoxyphenyl)methyl>dihydro-3-hydroxy-2(3H)-furanone 
• 33464-73-2 3,4-bis<(3,4-dimethoxyphenyl)methyl>dihydro-3-hydroxy-2(3H)-furanone 
• 580-72-3 (2RS,3RS)-2,3-bis-(4-hydroxy-3-methoxybenzyl)butyrolactone 
• 116185-15-0 dihydro-3-hydroxy-3,4-bis<<3-methoxy-4-(phenylmethoxy)phenyl>methyl>-2,(3H)-furanone 

Relevant articles and documents

A novel approach towards dibenzylbutyrolactone lignans involving heck and radical reactions: Application to (±)-matairesinol synthesis

A highly regio- and stereoselective Heck reaction of iodoarenes with vinylated malonates, generated in situ by fluoride-induced protiodesilylation of alkenylsilanols/disiloxanes to give functionalized styrenes and 1,4-diaryl-1-butenes has been developed. The dibenzylbutyrolactone lignan skeletons have been achieved from 1,4-diaryl-1-butenes by two routes involving diastereoselective radical cyclization as the key step. This strategy has successfully been applied in the synthesis of (±)-matairesinol. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.