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1135-24-6

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Ferulic acid
Cas No: 1135-24-6
USD $ 90.0-100.0 / Kilogram 1 Kilogram 5000 Kilogram/Month Kono Chem Co.,Ltd Contact Supplier
Corey Ferulic Acid
Cas No: 1135-24-6
USD $ 1.0-1.0 / Kilogram 1 Kilogram 10 Metric Ton/Month Career Henan Chemical Co Contact Supplier
Ferulic acid CAS 1135-24-6 IN Stock 4-Hydroxy-3-methoxycinnamic acid CAS 1135-24-6
Cas No: 1135-24-6
USD $ 1.0-1.0 / Kilogram 1 Kilogram 800 Metric Ton/Year Chemwill Asia Co., Ltd. Contact Supplier
Ferulic Acid
Cas No: 1135-24-6
USD $ 45.0-50.0 / Kilogram 1 Kilogram 1 Kilogram/Day DB BIOTECH CO., LTD Contact Supplier
Ferulic acid
Cas No: 1135-24-6
No Data 1 Kilogram 1000 Metric Ton/Month Haihang Industry Co.,Ltd. Contact Supplier
Ferulic acid
Cas No: 1135-24-6
No Data 1 Kilogram 5 Metric Ton/Month MedicalChem(Yancheng)Manuf.Co.,Ltd. Contact Supplier
4-Hydroxy-3-methoxycinnamic acid
Cas No: 1135-24-6
No Data No Data No Data Cartoon Ingredients Co., Ltd Contact Supplier
4-Hydroxy-3-methoxycinnamic acid Manufacturer/High quality/Best price/In stock
Cas No: 1135-24-6
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
Ferulic Acid rice bran extract
Cas No: 1135-24-6
USD $ 16.0-16.0 / Kilogram 1 Kilogram 3000 Kilogram/Month Greenutra Resource Inc Contact Supplier
API/Pharmaceutical Raw Material Ferulic Acid 1135-24-6
Cas No: 1135-24-6
No Data 10 Gram 1000 Metric Ton/Month Hubei Jusheng Technology Co., Ltd., Contact Supplier

1135-24-6 Usage

Uses

Widely distributed in small amounts in plants. Used as an antioxidant and food preservative

Plant sources

Ferulic acid is a kind of phenolic acid extracted from the resin of ferula asafetida. Ferula asafetida is a kind of Umbelliferae perennial herb with a strong garlic smell and living in sandy areas. It is mainly produced in Xinjiang. During the nascent stage, there are only root leaves. At 5 years, scape emerges. The scape is very strong with its height being up to two meters. At end spring and early summer (flowering stage to early fruit stage), apply slanting cut from the upper position down to the bottom separately, collect oozing milky resin, dry it. Ferula asafetida contains volatile oils, gums and resins with oil containing various kinds of organic acids such as (R)-sec-butyl-1-propenyl disulfide, 1(1-methylthio-propyl) 1-propenyl disulfide, sec-butyl 3-methylthio-allyl-disulfide. Resin containing ferulic acid and its related esters.
 Resina Ferulae
Figure 1 is Resina Ferulae

Lipid-Lowering effect

Ferulic acid can competitively inhibit the liver mevalonate-5-pyrophosphate dehydrogenase activity, inhibiting the synthesis of cholesterol in the liver, so as to achieve the purpose of lowering blood pressure.

Purification Methods

Crystallise ferulic acid from H2O. [Beilstein 10 H 436, 10 IV 1776.]

Antimicrobial effect

Ferulic acid exhibits a broader anti-bacterial spectrum. It has been found that ferulic acid is able to inhibit pathogenic bacteria such as Shigella sonnei, Klebsiella pneumoniae, Enterobacter, Escherichia coli, Citrobacter, Pseudomonas aeruginosa and 11 kinds of microorganisms which causing food corruption.

Uses

antineoplastic, choleretic, food preservative

Food Industry Applications

In addition to its wide application in medicine, ferulic acid has been approved by some countries to be as a food additive. Japan has approved it to be used in food antioxidants while the United States and some European countries have allowed for adopting some kinds of herbs, coffee, beans with relative high amount of ferulic acid for being antioxidant. Ferulic acid, in the food industry, is mainly used for the preparation of natural vanillin, antioxidants, preservatives, cross-linkers and functional promoting agent. The information is edited by Xiaonan from Chemicalbook.

Synthetic method

Ferulic acid can be obtained through chemical synthesis and extraction. Laboratory dissolves the vanillin, malonic acid and piperidine in pyridine for reaction of three weeks after which with hydrochloric acid precipitation, you can obtain ferulic acid.
 laboratory synthesis roadmap of ferulic acid
Figure 2 laboratory synthesis roadmap of ferulic acid

Physical and Chemical Properties

Ferulic acid is an aromatic acid widely being presented in plant kingdom and is the components of suberin. It amount is very small presented in plants in its free state but with its main form in forming bound state with oligosaccharides, polyamines, lipids and polysaccharides. It has many health functions, such as free radical scavenging, anti-thrombotic, anti-inflammatory, anti-tumor, prevention and treatment of hypertension, heart disease, and enhanced sperm activity and so on. Ferulic acid has a low toxicity and is easy for being metabolized by human. It can be used as a food preservative and has a wide range of applications in the field of food and medication.
The above information is edited by the chemicalbook of Yan Yanyong.

Pharmacological effects

Ferulic acid has various effects of inhibiting platelet aggregation, expectorant, and inhibition of Mycobacterium tuberculosis and so on. Clinically ferulic acid is mainly applied to the adjuvant treatment of various kinds of vascular diseases such as atherosclerosis, coronary heart disease, cerebrovascular, renal disease, pulmonary hypertension, diabetic vascular disease, and vasculitis as well as neutropenia and thrombocytopenia. It can be used for treating migraine and vascular headache. As a leukocyte-enhancement drug, this drug also has enhanced hematopoietic function. Therefore, ferulic acid may also be for the treatment of leukopenia and thrombocytopenia.
Reference: Xu Jingfeng, Yang Ming (editor) Handbook of clinical prescription drugs. Nanjing: Jiangsu Science and Technology Press .2009 on page 561.

Uses

anti-oxidant, anti-inflammatory, sunscreen enhancer

Uses

It can be used as a food preservative and a kind of organic chemicals.
It can be used as the intermediates of cinametic acid. It can also be used as food preservative.
It can also be applied to biochemical studies

Chemical Properties

Pale Yellow Solid
InChI:InChI=1/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/p-1/b5-3+

1135-24-6 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
USP (1270311)  Ferulic acid  United States Pharmacopeia (USP) Reference Standard 1135-24-6 1270311-25MG 4,326.66CNY Detail

1135-24-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name ferulic acid

1.2 Other means of identification

Product number -
Other names FERULIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Food additives -> Flavoring Agents
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1135-24-6 SDS

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