1162674-13-6

Basic information

• Product Name: 2-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)acetic acid
• Synonyms: 2-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)acetic acid
• CAS NO: 1162674-13-6
• Molecular Weight: 259.262
• Mol File: 1162674-13-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)acetic acid(1162674-13-6)
• EPA Substance Registry System: 2-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)acetic acid(1162674-13-6)

Safety Data

• Hazardous Substances Data: 1162674-13-6(Hazardous Substances Data)

Upstream product

• 1963-43-5 (4-methoxyphenyl)(1H-pyrrol-2-yl)methanone 
• 1449787-62-5 ethyl {2-[(4-methoxyphenyl)carbonyl]-1H-pyrrol-1-yl}acetate 

Relevant articles and documents

1-Hydroxypyrazole as a bioisostere of the acetic acid moiety in a series of aldose reductase inhibitors

Therapeutic intervention with aldose reductase inhibitors appears to be promising for major pathological conditions (i.e., long-term diabetic complications and inflammatory pathologies). So far, however, clinical candidates have failed due to adverse side-effects (spiroimides) or poor bioavailability (carboxylic acids). In this work, we succeeded in the bioisosteric replacement of an acetic acid moiety with that of 1-hydroxypyrazole. This new scaffold appears to have a superior physicochemical profile, while attaining inhibitory activity in the submicromolar range.