1963-43-5

Basic information

• Product Name: Methanone, (4-methoxyphenyl)-1H-pyrrol-2-yl-
• Synonyms: 2-(4-methoxybenzoyl)pyrrole;(4-Methoxy-phenyl)-(1H-pyrrol-2-yl)-methanone;2-(p-methoxybenzoyl)pyrrole;pyrrol-2-yl 4-methoxyphenyl ketone;(4-methoxy-phenyl)(1H-pyrrol-2-yl)methanone;(1H-Pyrrol-2-yl)-[4-(methoxy)phenyl] ketone;(4-methoxy-phenyl)-pyrrol-2-yl-methanone
• CAS NO: 1963-43-5
• Molecular Formula: C12H11NO2
• Molecular Weight: 201.225
• Mol File: 1963-43-5.mol
• Article Data: 23

Chemical Properties

• Melting Point: 114 - 116 °C
• CAS DataBase Reference: Methanone, (4-methoxyphenyl)-1H-pyrrol-2-yl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (4-methoxyphenyl)-1H-pyrrol-2-yl-(1963-43-5)
• EPA Substance Registry System: Methanone, (4-methoxyphenyl)-1H-pyrrol-2-yl-(1963-43-5)

Safety Data

• Hazardous Substances Data: 1963-43-5(Hazardous Substances Data)

Upstream product

• 109-97-7 pyrrole 
• 100-07-2 4-methoxy-benzoyl chloride 
• 132371-46-1 2-[2-(4-Methoxy-phenyl)-benzo[1,3]dithiol-2-yl]-1H-pyrrole 
• 112816-53-2 2-[2-(4-Methoxy-phenyl)-benzo[1,3]oxathiol-2-yl]-1H-pyrrole 
• 100-09-4 4-methoxybenzoic acid 
• 58948-36-0 2-(4-Methoxyphenyl)-1,3-benzoxathiolium tetrafluoroborate 
• 20671-52-7 lithium pyrrolide 
• 123-11-5 4-methoxy-benzaldehyde 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 7099-91-4 p-methoxybenzoylformic acid 
• 38480-28-3 2-bromo-1H-pyrrole 
• 105-13-5 4-Methoxybenzyl alcohol 
• 7504-58-7 N-(4-methoxybenzoyl)morpholine 

Downstream Products

• 1449787-62-5 ethyl {2-[(4-methoxyphenyl)carbonyl]-1H-pyrrol-1-yl}acetate 
• 1162674-13-6 2-(2-(4-methoxybenzoyl)-1H-pyrrol-1-yl)acetic acid 
• 24064-16-2 benzyl 2-[(4-methoxyphenyl)methyl]-2,5-dihydropyrrole-1-carboxylate 
• 22862-67-5 2-[(4-methoxyphenyl)methyl]-2,5-dihydro-(1H)-pyrrole 
• 50499-44-0 (4,5-dichloro-pyrrol-2-yl)-(4-methoxy-phenyl)-methanone 
• 397325-77-8 [1-(2-propenyl)-1H-pyrrol-2-yl] [4-methoxyphenyl] ketone 
• 152999-90-1 (5-{[5-(Hydroxy-phenyl-methyl)-1H-pyrrol-2-yl]-p-tolyl-methyl}-1H-pyrrol-2-yl)-(4-methoxy-phenyl)-methanol 
• 152999-89-8 1-p-Anisoyl-9-benzoyl-5-p-tolyldipyrromethane 
• 152999-88-7 2-p-Anisoyl-5-<(4-tolyl)hydroxymethyl>pyrrole 
• 132313-41-8 5-(4-Fluoro-3-methylphenyl)-10-(4-methoxyphenyl)-15-(4-tolyl)-20-phenylporphyrin 
• 132313-39-4 5,15-bis-(4-methylphenyl)-10,20-diphenyl-porphyrin 
• 132362-77-7 5-(4-Fluoro-3-methylphenyl)-1-<(4-methoxyphenyl)hydroxymethyl>dipyrromethane 
• 132313-37-2 5-(4-Fluoro-3-methylphenyl)-1-(4-methoxybenzoyl)dipyrromethane 
• 132313-35-0 2-<(4-Fluoro-3-methylphenyl)hydroxymethyl>-5-(4-methoxybenzoyl)pyrrole 

Relevant articles and documents

Synthesis method of 2-aromatic acyl pyrrole compounds

The invention relates to the field of organic synthesis, and discloses a synthesis method of 2-aromatic acyl pyrrole compounds, wherein the synthesis method comprises the steps: taking an N-aromatic acyl pyrrole compound as a raw material, and carrying ou

Aroylation of Electron-Rich Pyrroles under Minisci Reaction Conditions

The development of Minisci acylation on electron-rich pyrroles under silver-free neutral conditions has been reported featuring the regioselective monoacylation of (NH)-free pyrroles. Unlike conventional Minisci conditions, the avoidance of any acid that could result in the polymerization of pyrroles was the key to success. The umpolung reactivity of the nucleophilic acyl radical, generated in situ from arylglyoxylic acid, could help explain the mechanism of product formation with electron-rich pyrroles. Alternatively, the nucleophilic substitution of the acyl radical on the electron-deficient pyrrole radical cation is proposed.

Synthesis of 2-benzoylpyrrole derivatives via C-H functionalization adjacent to nitrogen of pyrrole

A direct transition-metal-free synthesis of 2-benzoylpyrrole derivatives from free (N-H) pyrroles and benzaldehyde has been developed. The benzoylation reaction at the 2 or 5-position of pyrrole proceeded well under the alkali metalation system and with 2