116324-76-6

Basic information

• Product Name: 3,5-Pyridinedicarboxylic acid, 4-[3-(acetyloxy)phenyl]-1,4-dihydro-2,6-dimethyl-, dimethyl ester
• CAS NO: 116324-76-6
• Molecular Formula: C19H21NO6
• Molecular Weight: 359.379
• Mol File: 116324-76-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,5-Pyridinedicarboxylic acid, 4-[3-(acetyloxy)phenyl]-1,4-dihydro-2,6-dimethyl-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Pyridinedicarboxylic acid, 4-[3-(acetyloxy)phenyl]-1,4-dihydro-2,6-dimethyl-, dimethyl ester(116324-76-6)
• EPA Substance Registry System: 3,5-Pyridinedicarboxylic acid, 4-[3-(acetyloxy)phenyl]-1,4-dihydro-2,6-dimethyl-, dimethyl ester(116324-76-6)

Safety Data

• Hazardous Substances Data: 116324-76-6(Hazardous Substances Data)

Upstream product

• 34231-78-2 3-formylphenyl acetate 
• 105-45-3 acetoacetic acid methyl ester 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINES AND NOVEL 1,4-DIHYDROPYRIDINES USEFUL AS THERAPEUTIC AGENTS

The present invention provides a process for the preparation of 1,4-dihydropyridines of the formula (1), wherein R1 is H, NO2, Cl, OAc, OH, R2 is H, NO2, Cl, -O-CH2-O-, OMe, OAc, OEt, OH, R3 is H, NO2, Cl, N(Me)2, -O- CH2 -O-, OMe, OAc, OH, R4 is H, OMe, OAc, OH, R5 is H, Cl, I, and R6 and R7 are either methyl, ethyl or both by preparing a mixture of an aromatic aldehyde, alkyl acetoacetate and a source of ammonia, adsorbing the prepared mixture and adsorbent till adsorbent becomes free flowing, heating the material so obtained under microwave irradiation, cooling the reaction mixture and recovering the compound of formula (1). The present invention also relates to novel 1,4-dihydropyridines with cardiovascular activity.