34231-78-2

Basic information

• Product Name: 3-ACETOXYBENZALDEHYDE
• Synonyms: 3-FORMYLPHENYLACETATE;3-ACETOXYBENZALDEHYDE;M-FORMYL PHENYL ACETATE;3-Acetoxybenzaldehyde 97%;3-ACETOXYBENZALDEHYDE / 3-FORMYLPHENYL ACETATE;m-Acetoxybenzaldehyde;Acetoxybenzaldehyde;3-Formylphenyl Acetate Acetic Acid 3-Formylphenyl Ester
• CAS NO: 34231-78-2
• Molecular Formula: C₉H₈O₃
• Molecular Weight: 164.16
• EINECS: 251-890-4
• Product Categories: Aromatic Aldehydes & Derivatives (substituted)
• Mol File: 34231-78-2.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 138°C 20mm
• Flash Point: 138°C/20mm
• Appearance: /
• Density: 1,17 g/cm3
• Refractive Index: 1.5330
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility: Insoluble in water.
• Sensitive: Air Sensitive
• BRN: 1941499
• CAS DataBase Reference: 3-ACETOXYBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ACETOXYBENZALDEHYDE(34231-78-2)
• EPA Substance Registry System: 3-ACETOXYBENZALDEHYDE(34231-78-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 34231-78-2(Hazardous Substances Data)

Usage

Uses

3-Acetoxybenzaldehyde, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It is also used as an intermediate in organic synthesis.

Upstream product

• 108-24-7 acetic anhydride 
• 100-83-4 meta-hydroxybenzaldehyde 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 111342-08-6 3-(dibromomethyl)phenyl acetate 
• 75-36-5 acetyl chloride 
• 6304-89-8 3-acetoxybenzoic acid 
• 60-29-7 diethyl ether 

Downstream Products

• 25673-60-3 trans-3-(3-acetoxybenzylidene)-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione 
• 25673-61-4 1-acetyl-trans-3-(3-acetoxybenzylidene)-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione 
• 17188-37-3 Acetic acid 3-[(2,4-dinitro-phenoxyimino)-methyl]-phenyl ester 
• 64-19-7 acetic acid 
• 100-83-4 meta-hydroxybenzaldehyde 

Relevant articles and documents

3-/4-ester substituted benzaldehyde thiosemicarbazone derivatives as well as preparation and application thereof

The invention belongs to the technical field of tyrosinase inhibitors, and discloses 3-/4-ester substituted benzaldehyde thiosemicarbazone derivatives as well as preparation and an application thereof. The 3-/4-ester substituted benzaldehyde thiosemicarbazone derivatives have a structural formula represented by a formula I shown in the description, wherein RCOO- is used as a 3-position substituentor 4-position substituent, and R is alkyl, phenyl or benzyl. The 3-/4-ester substituted benzaldehyde thiosemicarbazide derivatives provided by the invention are used as the tyrosinase inhibitors, andused for preparation of a medicine for treating Parkinson syndrome and an anti-melanoma medicine, and preparation of whitening cosmetics, biological insecticides and food preservatives. The 3-/4-ester substituted benzaldehyde thiosemicarbazone derivatives provided by the invention are extremely simply synthesized, and can be obtained only through a simple esterification reaction and a Schiff basereaction; and meanwhile the 3-/4-ester substituted benzaldehyde thiosemicarbazone derivatives provided by the invention have better activity, and have strong inhibitory activity against tyrosinase.

Chemoselective reduction of the carbonyl functionality through hydrosilylation: Integrating click catalysis with hydrosilylation in one pot

Herein we report the chemoselective reduction of the carbonyl functionality via hydrosilylation using a copper(I) catalyst bearing the abnormal N-heterocyclic carbene 1 with low (0.25 mol %) catalyst loading at ambient temperature in excellent yield within a very short reaction time. The hydrosilylation reaction of α,β-unsaturated carbonyl compounds takes place selectively toward 1,2-addition (C=O) to yield the corresponding allyl alcohols in good yields. Moreover, when two reducible functional groups such as imine and ketone groups are present in the same molecule, this catalyst selectively reduces the ketone functionality. Further, 1 was used in a consecutive fashion by combining the Huisgen cycloaddition and hydrosilylation reactions in one pot, yielding a range of functionalized triazole substituted alcohols in excellent yields.