116376-82-0Relevant academic research and scientific papers
Tandem 1,6-addition/cyclization/vinylcyclopropane rearrangement at low temperature under metal-free conditions: an approach to spiro[4.5]cyclohexadienones
Yuan, Zhenbo,Gai, Kuo,Wu, Youzhi,Wu, Jie,Lin, Aijun,Yao, Hequan
supporting information, p. 3485 - 3488 (2017/03/30)
A tandem 1,6-addition/cyclization/vinylcyclopropane rearrangement reaction (VCPR) of vinylogous para-quinone methides at low temperature under metal-free conditions has been disclosed for the first time. This method provides an efficient strategy for the construction of a range of spiro[4.5]cyclohexadienones in good yield, exhibiting good functional group tolerance as well as gram-scale capacity.
Antiinflammatory 2,6-Di-tert-butyl-4-(2-arylethenyl)phenols
Lazer, Edward S.,Wong, Hin-Chor,Possanza, Genus J.,Graham, Anne G.,Farina, Peter R.
, p. 100 - 104 (2007/10/02)
A series of 2,6-di-tert-butyl-4-(2-arylethenyl)phenols was prepared and examined for their ability to inhibit cyclooxygenase and 5-lipoxygenase in vitro and developing adjuvant arthritis in vivo in the rat.Structure-activity relationships are discussed.Am
