116388-35-3Relevant academic research and scientific papers
Cu-Catalyzed Oxidation of C2 and C3 Alkyl-Substituted Indole via Acyl Nitroso Reagents
Zhang, Jun,Torabi Kohlbouni, Saeedeh,Borhan, Babak
, p. 14 - 17 (2019/01/08)
The selective oxidation of C2-alkyl-substituted indoles to 3-oxindole and the selective C-H oxygenation or amination of C2,C3-dialkyl-substituted indoles at C2 are reported under mild conditions. The position of the alkyl substitution on the indole directs the reaction to different pathways under similar conditions.
SYNTHESIS OF INDOLES FROM PYRIDINIUM SALTS 5. SECONDARY AMINES IN THE REACTION OF 3-NITROPYRIDINIUM SALTS WITH ACETONE
Yurkovskaya, M. A.,Afanas'ev, A. Z.,Chertkov, V. A.,Bundel', Yu. G.
, p. 1000 - 1008 (2007/10/02)
The use of secondary amines in the reaction of 3-nitropyridinium salts with acetone makes it possible to isolate stable intermediates in the formation of indoles - (o-N,N-dialkylaminobenzyl)ketones - and to observe new reaction pathways - the formation of bisindolylpropanes and p-nitroanilines.
SYNTHESIS OF INDOLES FROM PYRIDINIUM SALTS. 4. KETIMINES IN THE SYNTHESIS OF INDOLES FROM 3-NITROPYRIDINIUM SALTS
Yurovskaya, M. A.,Afanas'ev, A. Z.,Chertkov, V. A.,Gizatullina, E. M.,Bundel', Yu. G.
, p. 1305 - 1308 (2007/10/02)
The possibility of using certain ketimines in place of mixtures of ketone and amine in the synthesis of indoles from 3-nitropyridinium salts has been demonstrated.The use of ketimines leads, in many cases, to increased yields of indoles and simplifies their isolation.It has been established that the rate of indole formation is considerably increased in polar aprotic solvents.
