1164112-38-2

Upstream product

• 80466-79-1 isoxazole-4-sulfonyl chloride 
• 115-46-8 C₁₈H₂₁NO 
• 100-58-3 phenylmagnesium bromide 
• 14548-46-0 4-Benzoylpyridine 
• 20735-04-0 (1,2,3,6-tetrahydro-1-methylpyridin-4-yl)diphenylmethanol 
• 6071-92-7 VUF 4589 
• 1620-30-0 diphenyl(pyridin-4-yl)methanol 
• 112818-77-6 ethyl 4-(hydroxydiphenylmethyl)piperidine-1-carboxylate 

Relevant academic research and scientific papers

Synthesis, Characterization, Crystal, and Molecular Structure Studies of [1-(3,5-Dimethyl-2,3-dihydro-isoxazole-4-sulfonyl)-piperidin-4-yl}-diphenyl-methanol

The title compound [1-(3,5-Dimethyl-2,3-dihydro-isoxazole-4-sulfonyl)-piperidin-4-yl)-diphenyl-methanol was synthesized and the product obtained was characterized by spectroscopic techniques and finally the structure was confirmed by X-ray diffraction stu

Synthesis and in vitro antiproliferative activity of diphenyl(sulphonylpiperidin-4-yl)methanol derivatives

A series of novel diphenyl(piperidin-4-yl)methanol derivatives 10(a-n) were synthesized and characterized by 1H NMR, LC/MS, FTIR, and elemental analyses. All the synthesized compounds were evaluated for cell proliferation by MTT assay. The antiproliferative effects of the synthesized compounds were tested against viable human skin fibroblast cell line and carcinoma cell lines, namely HeLa cells, HT-29 cells, MCF-7 cells, and HepG-2 cells in comparing the positive and negative control. Among the synthesized compounds, (10b) and (10g) have been identified as potent antiproliferative agents.