80466-79-1

Basic information

• Product Name: 3,5-DIMETHYLISOXAZOLE-4-SULFONYL CHLORIDE
• Synonyms: AKOS BBS-00002878;AKOS PAO-1613;AKOS B020507;DMISC;BUTTPARK 27\06-15;ART-CHEM-BB B020507;4-Isoxazolesulfonylchloride,3,5-dimethyl-(9CI);3,5-Dimethylisoxazole-4-sulfonyl chloride ,97%
• CAS NO: 80466-79-1
• Molecular Formula: C₅H₆ClNO₃S
• Molecular Weight: 195.62
• Product Categories: SULFONYLHALIDE
• Mol File: 80466-79-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: 39-40°C
• Boiling Point: 310.8 °C at 760 mmHg
• Flash Point: 141.7 °C
• Appearance: /
• Density: 1.452 g/cm³
• Vapor Pressure: 0.00108mmHg at 25°C
• Refractive Index: 1.504
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -4.42±0.28(Predicted)
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 3,5-DIMETHYLISOXAZOLE-4-SULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIMETHYLISOXAZOLE-4-SULFONYL CHLORIDE(80466-79-1)
• EPA Substance Registry System: 3,5-DIMETHYLISOXAZOLE-4-SULFONYL CHLORIDE(80466-79-1)

Safety Data

• Hazard Codes: Xi
• Statements: 34-36
• Safety Statements: 26-27-36/37/39-45
• RIDADR: 3261
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 80466-79-1(Hazardous Substances Data)

Usage

Chemical Properties

White to off-white solid

InChI:InChI=1/C5H6ClNO3S/c1-3-5(11(6,8)9)4(2)10-7-3/h1-2H3

Upstream product

• 300-87-8 3,5-dimethyl-1,2-oxazole 

Downstream Products

• 80466-89-3 N-(4-chlorophenyl)-3,5-dimethyl-4-isoxazolesulfonamide 
• 17605-87-7 1-(3,5-dimethyl-isoxazole-4-sulfonyl)-3,5-dimethyl-1H-pyrazole 
• 80467-04-5 C₁₂H₁₂ClN₃O₃S 
• 80467-23-8 C₁₂H₁₃N₃O₄S 
• 80467-02-3 C₁₃H₁₅N₃O₄S 
• 80467-03-4 C₁₄H₁₈N₄O₃S 
• 80467-05-6 C₁₂H₁₁Cl₂N₃O₃S 
• 80467-30-7 C₁₅H₁₇N₃O₄S 
• 80467-43-2 4-(3,5-Diphenyl-pyrazole-1-sulfonyl)-3,5-dimethyl-isoxazole 
• 80467-32-9 C₂₀H₁₉N₃O₄S 
• 80467-24-9 C₁₉H₁₇N₃O₅S 
• 1164112-38-2 (1-(3,5-dimethyl-2,3-dihydro-isoxazole-4-sulfonyl)-piperidin-4-yl)-diphenyl-methanol 
• 958741-19-0 (S)-2-(3,5-Dimethylisoxazol-4-ylsulfonyl)-8-methyl-6-phenyl-2,3,4,7,8,10-hexahydro-1H-pyrano[4,3-c][1,6]naphthyridine 
• 1268486-73-2 C₂₀H₂₁FN₂O₄S 

Relevant articles and documents

Development of novel NLRP3-XOD dual inhibitors for the treatment of gout

Gout is a crystalline-related arthropathy caused by the deposition of monosodium urate (MSU). Acute gouty arthritis is the most common first symptom of gout. Studies have shown that NOD-like receptor protein 3 (NLRP3) inflammasome as pattern recognition r

Bispiperidines as antithrombotic agents

Novel compounds which are inhibitors of the binding of fibrinogen to the Gp IIb/IIIa platelet receptors, and which can be used therepeutically as antithrombotic agents

Some Heterocyclic Sulfonyl Chlorides and Derivatives

The syntheses of 4- and 5-chlorosulfonylfuran-2-carboxylic acid (Ia,IIa), 4-chlorosulfonylfuran-2-carboxamide (Ib), 3,5-dimethylpyrazole and isoxazole-4-sulfonyl chlorides (IIa, IVa) and 2,4-dimethylthiazole-5-sulfonyl chloride (Va) are described.The sulf