116436-23-8

Basic information

• Product Name: Bis-(3-dimethylamino-phenyl)-phenyl-methanol
• CAS NO: 116436-23-8
• Molecular Weight: 346.472
• Mol File: 116436-23-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Bis-(3-dimethylamino-phenyl)-phenyl-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: Bis-(3-dimethylamino-phenyl)-phenyl-methanol(116436-23-8)
• EPA Substance Registry System: Bis-(3-dimethylamino-phenyl)-phenyl-methanol(116436-23-8)

Safety Data

• Hazardous Substances Data: 116436-23-8(Hazardous Substances Data)

Upstream product

• 93-58-3 benzoic acid methyl ester 
• 86967-66-0 (3-(dimethylamino)phenyl)magnesium bromide 
• 96138-88-4 Michler ketone 
• 98-95-3 nitrobenzene 
• 611-79-0 3,3'-diaminobenzophenone 
• 619-25-0 3-Nitrobenzyl alcohol 
• 21222-05-9 3,3'-dinitrobenzophenone 

Downstream Products

• 1310449-95-6 3,3'-(phenyl(3-phenylpropoxy)methylene)bis(N,N-dimethylaniline) 

Relevant articles and documents

Development of trityl-based photolabile hydroxyl protecting groups

A series of trityl-based photolabile hydroxyl protecting groups have been examined. These PPGs evolve from the traditional acid-labile trityl protecting group with proper electron-donating substituents. Structure-reactivity relationships have been explored. A m-dimethylamino group is crucial to achieve high photochemical deprotection efficiency. The o-hydroxyl group in 8 greatly improves the yield of the photochemical deprotection reaction, compared with the corresponding o-methoxyl-substituted counterpart 7. However, comparison between the photoreactions of 9 and 11 does not show similar structural relevance. The PPG in ether 1 (i.e., DMATr group) is structurally simple and easy to prepare and install. Its deprotection can be successfully carried out with irradiation of sunlight without requirement of photochemical devices.