116447-39-3

Basic information

• Product Name: methyl 2,3-methanopyroglutamate
• CAS NO: 116447-39-3
• Molecular Weight: 155.153
• Mol File: 116447-39-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2,3-methanopyroglutamate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,3-methanopyroglutamate(116447-39-3)
• EPA Substance Registry System: methyl 2,3-methanopyroglutamate(116447-39-3)

Safety Data

• Hazardous Substances Data: 116447-39-3(Hazardous Substances Data)

Upstream product

• 116447-36-0 methoxycarbonylmethyl-3-benzyloxycarbamide-3-carbomethoxy-Δ¹-pyrazoline 
• 116447-37-1 dimethyl N-benzyloxycarbonyl-2,3-methanoglutamate 
• 96658-30-9 methyl γ-methyl-α-(N-benzyloxycarbonyl)-α-dehydroglutamate 
• 13192-04-6 dimethyl 2-ketoglutarate 

Downstream Products

• 120083-45-6 2,3-methanopyroglutamic acid N-methyl amide 
• 116447-40-6 2,3-methanopyroglutamic acid 

Relevant articles and documents

THE SYNTHESIS AND CHARACTERIZATION OF 2,3-METHANOPYROGLUTAMIC ACID

Details of the synthesis of 2,3-methanopyroglutamic acid (1), its N-methylamide (7) and N-β-naphthylamide (6) are reported.An NMR study of the conformation of 7 is discussed and the stability of the amide 6 to pyroglutamylaminopeptidase is detailed.The crystal structure of an alkene (4) formed during the pyrolysis of an intermediate pyrazoline (2) indicates that the (Z)-configuration is conserved during nitrogen extrusion.