116447-40-6

Basic information

• Product Name: 2,3-methanopyroglutamic acid
• Synonyms: 2,3-methanopyroglutamic acid
• CAS NO: 116447-40-6
• Molecular Formula: C6H7 N O3
• Molecular Weight: 141.12
• Mol File: 116447-40-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 464.7°Cat760mmHg
• Flash Point: 234.9°C
• Appearance: /
• Density: 1.621g/cm³
• Vapor Pressure: 6.33E-10mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 2,3-methanopyroglutamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-methanopyroglutamic acid(116447-40-6)
• EPA Substance Registry System: 2,3-methanopyroglutamic acid(116447-40-6)

Safety Data

• Hazardous Substances Data: 116447-40-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H7NO3/c8-4-1-3-2-6(3,7-4)5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)

Upstream product

• 145241-91-4 γ-methyl N-benzyloxycarbonyl-(Z)-2,3-methanoglutamic acid α-benzyl ester 
• 126484-94-4 3-Oxo-2-aza-bicyclo[3.1.0]hexane-1-carboxylic acid methyl ester 
• 145241-90-3 4-methoxycarbonylmethyl-3-benzyloxycarbonylamino-3-benzyloxycarbonyl-1-pyrazoline 
• 104754-53-2 N-benzyloxycarbonyl-α-benzyl-(Z)-α,β-dehydroglutamate 
• 116447-36-0 methoxycarbonylmethyl-3-benzyloxycarbamide-3-carbomethoxy-Δ¹-pyrazoline 
• 116447-37-1 dimethyl N-benzyloxycarbonyl-2,3-methanoglutamate 
• 116447-43-9 (Z)-2-Benzyloxycarbonylamino-pent-2-enedioic acid 
• 96658-30-9 methyl γ-methyl-α-(N-benzyloxycarbonyl)-α-dehydroglutamate 
• 13192-04-6 dimethyl 2-ketoglutarate 
• 116447-39-3 methyl 2,3-methanopyroglutamate 

Downstream Products

• 120083-45-6 2,3-methanopyroglutamic acid N-methyl amide 
• 185527-67-7 (-)-(Z)-2,3-methano-L-glutamic acid 
• 185527-67-7 (+)-(2R,3R)-2,3-methanoglutamic acid 

Relevant articles and documents

The resolution and absolute configuration of 2,3-methanopyroglutamic acid, 3-oxo-2-azabicyclo[3,1,0]hexane-1-carboxylic acid

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Synthesis of 2,3-Methano-glutamic and -pyroglutamic Acid

2,3-Methano-analogues of glutamic and pyroglutamic acid have been synthesized and the β-naphthylamide of the latter is shown to be stable to pyroglutamic amino peptidase; the crystal structure of the methyl pyroglutamate analogue has been determined.