116452-12-1Relevant articles and documents
Methode de synthese d'acides gras marques substitues ou non en α et en β
Apparu, Marcel,Comet, Michel,Leo, Pierre M.,Mathieu, Jean-Paul,Du Moulinet, Amaury,et al.
, p. 118 - 124 (2007/10/02)
2-Propyn-1-ol and the dibromides Br(CH2)nBr (n = 10-12) have been used as starting materials for the synthesis of α- and β-methyl-branched fatty acids (C16) labeled with 123I at the ω-position.The methyl groups are introduced through the use of the lithium salt of either propanoic or isobutyric acid.The synthesis of *IC6H5(CH2)14COOH and *IC6H5(CH2)12CH(CH3)CH2COOH have been achieved in the same way starting from phenylacetylene.In each case, the radioactive iodine atom is introduced by an I/*I exchange reaction.