1193721-67-3 Usage
Uses
Used in Pharmaceutical and Cosmetic Industries:
22,22,22-d3-docosanoic acid is used as a research compound for studying the basic nanostructure of stratum corneum lipid matrices. This is particularly relevant in the development of pharmaceutical and cosmetic products that target skin health and function. The isotopic labeling of the compound enables researchers to better understand the interactions between ceramides and other lipid components in the skin's outermost layer, leading to the development of more effective formulations.
Used in Neutron Diffraction Studies:
In the field of materials science, 22,22,22-d3-docosanoic acid is used as a labeled compound for neutron diffraction studies. The presence of deuterium atoms in the molecule allows for enhanced contrast and improved signal-to-noise ratio in neutron scattering experiments. This enables researchers to gain a deeper understanding of the structural properties and organization of lipid matrices, which can be applied to various applications, including the development of advanced materials and the study of biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 1193721-67-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,9,3,7,2 and 1 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1193721-67:
(9*1)+(8*1)+(7*9)+(6*3)+(5*7)+(4*2)+(3*1)+(2*6)+(1*7)=163
163 % 10 = 3
So 1193721-67-3 is a valid CAS Registry Number.
1193721-67-3Relevant articles and documents
Synthesis of ceramides NS and NP with perdeuterated and specifically ω deuterated N-acyl residues
Sonnenberger, Stefan,Lange, Stefan,Langner, Andreas,Neubert, Reinhard H.H.,Dobner, Bodo
, p. 531 - 542 (2016/11/06)
The synthesis of 12 deuterated ceramides with either a deuteration at the last carbon atom of the amide bound fatty acid or a perdeuterated fatty acid chain is described. The ceramides were prepared starting from sphingosine or phytosphingosine and ω deuterated or perdeuterated fatty acids with PyBOP as activating agent in high yields. For the synthesis of the specifically deuterated fatty acids, dicarboxylic acids were transformed into ω deuterated alkyl bromide, which was chain elongated with blocked ω bromo alcohols by copper catalyzed Grignard coupling. Oxidation of regenerated alcohol function yields the ω deuterated fatty acids.
