116491-50-0

Basic information

• Product Name: Benzenamine, 2-(1-hexynyl)-
• CAS NO: 116491-50-0
• Molecular Formula: C12H15N
• Molecular Weight: 173.258
• Mol File: 116491-50-0.mol
• Article Data: 63

Chemical Properties

• CAS DataBase Reference: Benzenamine, 2-(1-hexynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2-(1-hexynyl)-(116491-50-0)
• EPA Substance Registry System: Benzenamine, 2-(1-hexynyl)-(116491-50-0)

Safety Data

• Hazardous Substances Data: 116491-50-0(Hazardous Substances Data)

Upstream product

• 615-43-0 2-iodophenylamine 
• 693-02-7 hex-1-yne 
• 615-36-1 2-bromoaniline 
• 33589-44-5 copper(I) butylacetylenide 
• 125345-34-8 1-(hex-1-ynyl)-2-nitrobenzene 
• 577-19-5 2-nitrophenyl bromide 
• 104919-72-4 ethyl N-[2-(1-butynyl)phenyl]carbamate 

Downstream Products

• 462637-36-1 N-(2-(hex-1-yn-1-yl)phenyl)benzamide 
• 1034422-10-0 11-butyl-2-fluoro-5-phenylbenzo[i]phenanthridine 
• 1034422-08-6 11-butylbenzo[i]phenanthridine 
• 1197893-81-4 2-butyl-3-[1-(4-methylphenyl)-2-nitroethyl]-1H-indole 
• 1197893-78-9 2-butyl-3-(2-nitro-1-phenylethyl)-1H-indole 
• 1201632-34-9 1-(2-(hex-1-ynyl)phenyl)urea 
• 1224970-01-7 1-[2-(hex-1-ynyl)phenyl]-3-phenylurea 
• 1033002-38-8 C₁₉H₂₀N₂S 
• 1415332-72-7 2-butyl-1-(5-methyl-2-phenylbenzofuran-4-yl)-1H-indole 
• 87587-40-4 1-benzyl-2-butyl-1H-indole 
• 33844-17-6 1-(2-aminophenyl)hexane-1-one 
• 13228-37-0 2-butyl-1H-indole 

Relevant articles and documents

Convenient indole synthesis from ethynylanilines with a polymer-supported fluoride

The cyclization reaction of ethynylanilines having phenyl, alkyl, methoxy, cyano, chloro, and ethoxycarbonyl groups with (polystyrylmethyl)trimethylammonium fluoride in dry MeCN under an argon atmosphere at 100°C proceeded in good yields to give the corresponding indoles without affecting these functional groups. Moreover, the polymer-supported fluoride could be reused for the cyclization reaction when the deprotection reaction of the N-substituted indole with the fluoride ion on resin did not occur under the cyclization conditions.

Cyclization of 2-Alkynyldimethylaniline on Gold(I) Cationic and Neutral Complexes

The cyclization reaction of 2-(1-hexynyl)dimethylaniline (S) on gold(I) has been studied by NMR spectroscopy, in order to characterize the ion pair structure of the product, [LAuSc]BF4. The latter is a good model for the catalytic in

Metal-Free and syn-Selective Hydrohalogenation of Alkynes through a Pseudo-Intramolecular Process

A new metal-free hydrohalogenation method for alkynes has been developed, which proceeds through a pseudo-intramolecular process. In this reaction, ethynylaniline serves as a substrate to quantitatively form an anilinium salt upon treatment with hydrochloric acid. The spatial proximity facilitates the efficient electrophilic addition of HCl to the ethynyl group in syn-mode, affording the corresponding chloroalkene without overaddition. This protocol was applied to HBr and HI, and the corresponding bromo- and iodoalkenes were obtained, respectively. The obtained chloroalkene was converted to tri-substituted alkenes possessing different aryl/alkynyl groups through Pd-catalyzed cross-coupling reactions.

Catalytic Enantioselective Aminopalladation–Heck Cascade

Domino processes initiated by intramolecular nucleopalladation of alkynes have been developed into powerful synthetic tools for the synthesis of functionalized heterocycles. However, a catalytic enantioselective version of this class of reactions remains