116498-75-0

Upstream product

• 116498-72-7 (3S,5S)-3-(4'-methylbenzenethio)-5-(trimethylsilyl)cyclohexanone 
• 127911-56-2 (S)-(-)-3-tolylthio-5-trimethylsilyl-2-cyclohexenone 
• 116384-78-2 (+/-)-3-p-tolylthio-5-(trimethylsilyl)cyclohexanone 
• 116384-79-3 (+/-)-3-tolylthio-5-trimethylsilyl-2-cyclohexenone 
• 116384-80-6 3-Methyl-5-trimethylsilanyl-cyclohex-2-enone 
• 56917-71-6 5-trimethylsilyl-2-cyclohexanone 
• 116498-74-9 (R)-3-Methyl-5-trimethylsilanyl-cyclohex-2-enone 
• 4294-57-9 para-methylphenylmagnesium bromide 

Downstream Products

• 86505-48-8 (R)-3-methyl-3-(p-tolyl)cyclopentan-1-one 
• 116384-93-1 (3S,5R)-6-Hydroxy-3-methyl-3-p-tolyl-5-trimethylsilanyl-hexanoic acid methyl ester 
• 116384-94-2 (R)-3-Methyl-3-p-tolyl-hexanedioic acid dimethyl ester 
• 147295-36-1 (R)-4-Methyl-2-oxo-4-p-tolyl-cyclopentanecarboxylic acid methyl ester 
• 116384-92-0 (4S,6R)-4-Methyl-4-p-tolyl-6-trimethylsilanyl-oxepan-2-one 

Relevant academic research and scientific papers

CONSTRUCTION OF CHIRAL QUARTERNARY CARBON CENTERS USING 3-SUBSTITUTED 5-TRIMETHYLSILYL-2-CYCLOHEXENONES: SYNTHESIS OF (+)-α-CUPARENONE

1,4-Addition of Grignard reagents to 3-substituted 5-trimethylsilyl-2-cyclohexenones proceeded in a highly diastereoselective manner.By utilizing the reaction, (+)-α-cuparenone was synthesized starting from enantiomerically pure 3-p-tolylthio-5-(trimethyl