116548-03-9

Usage

Uses

Used in Pharmaceutical Industry:
2-Hydroxy-6-(trifluoromethyl)nicotinamide is used as a pharmaceutical intermediate for its potential role in drug development and discovery. Its unique structure may contribute to the creation of new drugs with novel therapeutic properties.
Used in Organic Synthesis:
In the field of organic synthesis, 2-Hydroxy-6-(trifluoromethyl)nicotinamide is used as a key building block. Its presence of a hydroxyl and trifluoromethyl group allows for a variety of chemical reactions, making it instrumental in the synthesis of complex organic molecules for various applications.
Used in Chemical and Industrial Processes:
2-Hydroxy-6-(trifluoromethyl)nicotinamide is utilized as a versatile compound in chemical and industrial processes. Its properties may be harnessed to improve or create new processes in these industries, potentially leading to advancements in material science, chemical engineering, and related fields.

InChI:InChI=1/C7H5F3N2O2/c8-7(9,10)4-2-1-3(5(11)13)6(14)12-4/h1-2H,(H2,11,13)(H,12,14)

Upstream product

• 108-13-4 malonodiamide 
• 109317-78-4 4-n-butoxy-1,1,1-trifluorobut-3-en-2-one 
• 59938-06-6 4-ethoxy-1,1,1-trifluoro-3-butene-2-one 
• 59938-06-6 (E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one 
• 120407-73-0 4-butoxy-1,1,1-trifluoro-but-3-en-2-one 

Downstream Products

• 191595-63-8 2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylic acid 
• 144740-56-7 methyl 2-bromo-6-(trifluoromethyl)nicotinate 
• 191595-63-8 2-hydroxy-6-trifluoromethylnicotinic acid 

Relevant academic research and scientific papers

GHRELIN O-ACYLTRANSFERASE INHIBITORS

This invention relates to novel compounds according to Formula (I) which are inhibitors of ghrelin O-acyltransferase (GOAT), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment

USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS

According to the invention, compounds of the general formula (I) or salts thereof (pyridine-2-oxy-3-carboxamides), in which R1 is a (C1-C4)-haloalkyl radical can be employed as safeners, i.e. as agents for preventing or reducing phytotoxic effects of pesticides, preferably herbicides, on useful plants.

PYRIDONE DERIVATIVE AND HERBICIDE

[Object] To provide a pyridone derivative or an agriculturally acceptable salt thereof which enables control of various weeds growing in upland fields, orchards, paddy fields, and non-crop lands while showing a high safety to useful plants, useful crops,

ACYLATED SPIROPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS

Certain novel N-acylated spiropiperidine derivatives are ligands of the human melanocortin receptor(s) and, in particular, are selective ligands of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of MC-4R, such as obesity, diabetes, nicotine addiction, alcoholism, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.