1165626-74-3Relevant academic research and scientific papers
Synthesis of polysubstituted 3-aminoindenes: Via rhodium-catalysed [3+2] cascade annulations of benzimidates with alkenes
Wu, Binjie,Yang, Zi,Zhang, Hong,Wang, Lianhui,Cui, Xiuling
, p. 4190 - 4193 (2019)
A novel Rh-catalysed intermolecular [3+2] cascade cyclization of benzimidates and alkenes has been developed to assemble polysubstituted 3-aminoindenes. The target products are important building blocks for organic synthesis and drug discovery. Cheap and easily available α,β-unsaturated ketones or nitroalkenes are applied as coupling partners. Acyl or nitro groups are easily introduced to 3-aminoindenes at the C-2 position, which makes this reaction particularly attractive for further transformation to synthesize various important building blocks.
Rhodium-Catalyzed Cascade Annulation of Benzimidates and Nitroalkenes for the Synthesis of Difunctionalized Indenes
Lv, Ningning,Chen, Zhengkai,Liu, Yue,Liu, Zhanxiang,Zhang, Yuhong
supporting information, p. 4140 - 4146 (2019/08/02)
A facile and expeditious protocol for the synthesis of difunctionalized indenes from readily available benzimidates and nitroalkenes through rhodium-catalyzed C?H activation and cyclization is reported here. The transformation exhibits powerful reactivity
Synthetic method of 3-aminoindane compound
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Paragraph 0039-0050, (2019/11/12)
The invention discloses a synthetic method of a 3-aminoindane compound. The synthetic method comprises the following steps that an imine derivative, a nitroolefin compound, pentamethyl cyclopentadienerhodium dichloride, adamantane potassium formate are ad
Multi-substituted indene amine derivative and preparation method thereof
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Paragraph 0089; 0090; 0091, (2019/04/02)
The invention discloses a multi-substituted indene amine derivative and a preparation method thereof. The structural formula is shown in the description, wherein R1 is halogen, alkyl, aryl or alkoxy,R2 is aryl or alkyl, and R3 is acyl or nitryl. The inden
β-Nitrostyrenes as electrophiles in Parham cyclization chemistry: reaction with o-lithiobenzonitrile
Clarke, Adam J.,Hunt, David A.
body text, p. 2949 - 2951 (2009/08/07)
β-Nitrostyrenes react with o-lithiobenzonitrile, generated from the requisite aryl bromide at -100 °C by bromine-lithium exchange with n-butyllithium in THF, to afford 2-nitro-3-phenyl-3H-inden-1-ylamines resulting from 1,4-addition to the β-nitrostyrene
