116569-31-4Relevant academic research and scientific papers
METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND HAVING CARBOXYL GROUP
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Page/Page column 10, (2010/11/19)
To provide a novel method for producing an isothiocyanate compound having a carboxyl group(s) from the corresponding amino compound having a carboxyl group(s). A method for producing an isothiocyanate compound which has a carboxyl group(s) and is represented by the formula (2). And the method comprises reacting an amino compound which has a carboxyl group(s) and is represented by the formula (1) (wherein A is e.g. a C6-14 aromatic hydrocarbon group or a C1-12 saturated hydrocarbon group, and B is e.g. a single bond, a C6-14 aromatic hydrocarbon group or a C1-12 saturated hydrocarbon group), in a solvent, with carbon disulfide (CS2) and then with a halogen as a simple substance.
Thiocarbamoylation of amine-containing compounds 3. 5-(N′,N′-dimethylthioureido)salicylic acid. Synthesis and reactions
Van Boi, Luu,Al-Ebaisat
, p. 2290 - 2293 (2007/10/03)
Thiocarbamoylation of 5-aminosalicylic acid with tetramethylthiuram disulfide afforded 5-(N′,N′-dimethylthioureido)salicylic acid. Treatment of the latter with mineral acids or Ac2O gave 5-isothiocyanatosalicylic acid, whose reaction with ethan
