1165738-86-2

Basic information

• Product Name: 4-bromo-2-(2’-methylallyl)phenol
• Synonyms: 4-bromo-2-(2’-methylallyl)phenol
• CAS NO: 1165738-86-2
• Molecular Weight: 227.101
• Mol File: 1165738-86-2.mol

Chemical Properties

• CAS DataBase Reference: 4-bromo-2-(2’-methylallyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-(2’-methylallyl)phenol(1165738-86-2)
• EPA Substance Registry System: 4-bromo-2-(2’-methylallyl)phenol(1165738-86-2)

Safety Data

• Hazardous Substances Data: 1165738-86-2(Hazardous Substances Data)

Upstream product

• 5820-27-9 1-(2’-methylallyloxy)-4-bromobenzene 
• 106-41-2 4-bromo-phenol 

Downstream Products

• 5337-94-0 5-Bromo-2,2-dimethyl-2,3-dihydrobenzo[b]furan 
• 38002-92-5 2,3-dihydro-2,2-dimethylbenzofuran-5-carboxaldehyde 
• 1372769-03-3 4-bromo-1-cyanato-2-(2-methylallyl)benzene 

Relevant articles and documents

Catalytic Isohypsic-Redox Sequences for the Rapid Generation of Csp3-Containing Heterocycles

Cross-coupling reactions catalyzed by transition metals are among the most influential in modern synthetic chemistry. The vast majority of transition-metal-catalyzed cross-couplings rely on a catalytic cycle involving alternating oxidation and reduction o

LXR MODULATORS

The present invention provides compounds of Formula I: and pharmaceutically acceptable salts or solvates thereof, as modulators of liver X receptors (LXR), compositions comprising any of such novel compounds, methods of using these compounds or compositions as medicaments for prevention or treatment of diseases or disorders related to liver X receptor (LXR), as well as methods of preparing these LXR modulators and using them in the manufacture of medicaments.

Pyrimidine compounds and methods of making and using same

Disclosed herein are pyrimidinyl compounds that are contemplated to be modulators of cystic fibrosis transmembrane regulators (CFTR), and methods of making and using same. Also provided are pharmaceutical compositions and methods of treating disorders associated with cystic fibrosis transmembrane regulators, such as airway inflammation, cystic fibrosis, and the like.

Pd-Catalyzed intramolecular oxyalkynylation of alkenes with hypervalent iodine

(Figure presented) The first example of intramolecular oxyalkynylation of nonactivated alkenes using oxidative Pd chemistry is reported. Both phenol and aromatic or aliphatic acid derivatives could be used under operator-friendly conditions (room temperature, technical solvents, under air). The discovery of the superiority of benzlodoxolone-derlved hypervalent iodine reagent 3d as an alkyne transfer reagent further expands the rapidly increasing utility of hypervalent iodine reagents in catalysis and is expected to have important implications for other similar processes.

Design, synthesis, and biological evaluation of novel diarylalkyl amides as TRPV1 antagonists

We have developed a new class of diarylalkyl amides as novel TRPV1 antagonists. They exhibited potent 45Ca2+ uptake inhibitions in rat DRG neuron. In particular, the amide 59 was identified as a potent antagonist with IC50 of 57 nM. The synthesis and structure-activity relationship of the diarylalkyl amides are also described.