38002-92-5

Usage

Uses

Used in Pharmaceutical Industry:
2,2-DIMETHYL-2,3-DIHYDRO-BENZOFURAN-5-CARBALDEHYDE is used as a key intermediate in the synthesis of various pharmaceuticals due to its unique chemical structure and reactivity, facilitating the creation of diverse medicinal compounds.
Used in Fragrance Industry:
In the fragrance industry, 2,2-DIMETHYL-2,3-DIHYDRO-BENZOFURAN-5-CARBALDEHYDE is utilized as a component in the formulation of perfumes and scented products, capitalizing on its aromatic properties to enhance the olfactory experience.
Used in Flavor Industry:
2,2-DIMETHYL-2,3-DIHYDRO-BENZOFURAN-5-CARBALDEHYDE also serves as an ingredient in the development of flavors for food and beverages, leveraging its slightly sweet scent to contribute to the overall taste profile of these products.
Used in Organic Synthesis:
2,2-DIMETHYL-2,3-DIHYDRO-BENZOFURAN-5-CARBALDEHYDE is employed as a reactive intermediate in organic synthesis, allowing for the construction of complex organic molecules for a variety of applications across different industries.

InChI:InChI=1/C11H12O2/c1-11(2)6-9-5-8(7-12)3-4-10(9)13-11/h3-5,7H,6H2,1-2H3

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 5337-94-0 5-Bromo-2,2-dimethyl-2,3-dihydrobenzo[b]furan 
• 5820-27-9 1-(2’-methylallyloxy)-4-bromobenzene 
• 106-41-2 4-bromo-phenol 
• 1165738-86-2 4-bromo-2-(2’-methylallyl)phenol 

Downstream Products

• 1342890-64-5 N-cyclohexyl-N-((2,2-dimethyl-2,3-dihydrobenzofuran-5-yl)-methyl)-3,4-dimethoxybenzenesulfonamide 
• 1342890-65-6 N-cyclopentyl-N-((2,2-dimethyl-2,3-dihydrobenzofuran-5-yl)methyl)-3,4-dimethoxybenzenesulfonamide 

Relevant academic research and scientific papers

LXR MODULATORS

The present invention provides compounds of Formula I: and pharmaceutically acceptable salts or solvates thereof, as modulators of liver X receptors (LXR), compositions comprising any of such novel compounds, methods of using these compounds or compositions as medicaments for prevention or treatment of diseases or disorders related to liver X receptor (LXR), as well as methods of preparing these LXR modulators and using them in the manufacture of medicaments.

Design, synthesis, and biological evaluation of novel diarylalkyl amides as TRPV1 antagonists

We have developed a new class of diarylalkyl amides as novel TRPV1 antagonists. They exhibited potent 45Ca2+ uptake inhibitions in rat DRG neuron. In particular, the amide 59 was identified as a potent antagonist with IC50 of 57 nM. The synthesis and structure-activity relationship of the diarylalkyl amides are also described.

FUROISOQUINOLINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF

A compound having a partial structure represented by Formula: or a salt thereof has an excellent phosphodiesterase (PDE) IV-inhibiting effect, and is useful as a prophylactic or therapeutic agent against inflammatory diseases, for example, bronchial asthma, chronic obstructive pulmonary disease (COPD), rheumatoid arthritis, autoimmune disease, diabetes and the like.