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1165739-58-1

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1165739-58-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1165739-58-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,6,5,7,3 and 9 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1165739-58:
(9*1)+(8*1)+(7*6)+(6*5)+(5*7)+(4*3)+(3*9)+(2*5)+(1*8)=181
181 % 10 = 1
So 1165739-58-1 is a valid CAS Registry Number.

1165739-58-1Relevant articles and documents

Design, synthesis, and biological evaluation of novel diarylalkyl amides as TRPV1 antagonists

Li, Fu-Nan,Kim, Nam-Jung,Paek, Seung-Mann,Kwon, Do-Yeon,Min, Kyung Hoon,Jeong, Yeon-Su,Kim, Sun-Young,Park, Young-Ho,Kim, Hee-Doo,Park, Hyeung-Geun,Suh, Young-Ger

experimental part, p. 3557 - 3567 (2009/09/27)

We have developed a new class of diarylalkyl amides as novel TRPV1 antagonists. They exhibited potent 45Ca2+ uptake inhibitions in rat DRG neuron. In particular, the amide 59 was identified as a potent antagonist with IC50 of 57 nM. The synthesis and structure-activity relationship of the diarylalkyl amides are also described.

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