1165796-83-7Relevant academic research and scientific papers
Diastereoselective α-Sulfenylation of N- tert-Butanesulfinyl Imidates
Niu, Sheng-Tong,Liu, Hui,Xu, Yan-Jun,Lu, Chong-Dao
, p. 10580 - 10588 (2018)
A diastereoselective α-sulfenylation of chiral α-aryl/alkyl N-tert-butanesulfinyl imidates has been developed. Suitable sulfur electrophiles can be used as sulfenylating reagents to intercept aza-enolates generated from imidate deprotonation, giving α-thiofunctionalized imidates in good yields with high diastereocontrol. This protocol for C-S bond formation can efficiently synthesize enantioenriched 1,2-sulfanyl amine derivatives such as sulconazole.
Enantio- and diastereoselective addition of thioacetic acid to nitroalkenes via N-sulfinyl urea catalysis
Kimmel, Kyle L.,Robak, Maryann T.,Thomas, Stephen,Lee, Melissa,Ellman, Jonathan A.
scheme or table, p. 2704 - 2712 (2012/04/17)
The enantioselective addition of thioacetic acid to nitroalkenes was achieved using N-sulfinyl urea catalysis. In this report, the scope of the reaction was extended to the enantio- and diastereoselective thioacetic acid addition to cyclic α,β-disubstitut
Enantioselective addition of thioacetic acid to nitroalkenes via N-sulfinyl urea organocatalysis
Kimmel, Kyle L.,Robak, MaryAnn T.,Ellman, Jonathan A.
supporting information; experimental part, p. 8754 - 8755 (2009/12/04)
(Chemical Equation Presented) The highly enantioselective addition of thioacetic acid to nitroalkenes using a new sulfinyl urea organocatalyst is described. The addition of thioacetic acid proceeds in high yields and enantioselectivities for a variety of
