1165802-39-0Relevant academic research and scientific papers
New 8-hydroxyquinoline derivatives highlight the potential of this class for treatment of fungal infections
Abegg, Maxwel Adriano,Bazana, Luana Candice Genz,Fuentefria, Alexandre Meneghello,Gionbelli, Mariana Pies,Lopes, Marcela Silva,Reginatto, Paula,de Andrade, Saulo Fernandes,de Cesare, Maycon Antonio,Joaquim, Angélica Rocha,Kaminski, Taís Fernanda Andrzejewski,Teixeira, Mário Lettieri
, p. 18158 - 18170 (2021/10/12)
The oral administration of clioquinol - a potent 8-hydroxyquinoline antimicrobial drug - was forbidden due to suspicion of it being the cause of SMON (subacute myelo-optic-neuropathy) in Japan. However, this adverse effect was only observed in Japan, desp
First synthesis of 5- and 7-phenylethynyl-8-hydroxyquinolines by sonogashira reaction
Radchatawedchakoon, Widchaya,Promthong, Niwat,Sakee, Uthai
, p. 640 - 644 (2013/12/04)
5-Chloro-7-(2-phenylethynyl)quinolin-8-ol and 7-iodo-5-(2 -phenylethynyl)quinolin-8-ol was synthesized by Pd-CuI catalyzed Sonogashira-type cross-coupling of 8-(benzyloxy)-5-chloro-7-iodoquinoline and 8-(benzyloxy)-5,7- diiodoquinoline with 1-ethynylbenze
First Synthesis of 5-Chloro-7-[1,3]oxazolo[4,5-b]pyridin-2-ylquinolin-8-ol by Pd-Catalyzed Arylation
Sakee, Uthai,Grigg, Ronald
experimental part, p. 3031 - 3037 (2009/11/30)
5-Chloro-7-[1,3]oxazolo[4,5-b]pyridin-2-ylquinolin-8-ol was synthesized by a Pd-catalyzed arylation, which proceeds efficiently with 2 equivalents of benzylated clioquinol and 1 equivalent of oxazolo[4,5-b]pyridine. The product was smoothly debenzylated b
