116632-33-8

Basic information

• Product Name: 3-BroMo-5-nitroquinoline
• Synonyms: 3-BroMo-5-nitroquinoline
• CAS NO: 116632-33-8
• Molecular Formula: C₉H₅BrN₂O₂
• Molecular Weight: 253.0522
• EINECS: -0
• Mol File: 116632-33-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 203-205 °C
• Boiling Point: 325.0±0.0 °C(Predicted)
• Appearance: /
• Density: 1.747±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 0.35±0.23(Predicted)
• CAS DataBase Reference: 3-BroMo-5-nitroquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BroMo-5-nitroquinoline(116632-33-8)
• EPA Substance Registry System: 3-BroMo-5-nitroquinoline(116632-33-8)

Safety Data

• Hazardous Substances Data: 116632-33-8(Hazardous Substances Data)

Usage

General Description

3-Bromo-5-nitroquinoline is a chemical compound that belongs to the class of organic compounds known as quinolines. It is a yellow to brown crystalline solid that is used in the synthesis of pharmaceuticals and organic compounds. 3-BroMo-5-nitroquinoline is known for its chemical properties, as it can undergo various reactions such as nitration, halogenation, and reduction. It is also used as a building block in the production of other organic compounds and in the research and development of new materials. However, it is important to handle this chemical with caution as it may pose health and environmental risks if not properly managed.

Upstream product

• 607-34-1 5-nitroquinoline 
• 5332-24-1 3-bromoquinoline 

Downstream Products

• 116632-57-6 3-bromoquinolin-5-amine 
• 98589-84-5 5-nitro-[3]quinolylamine 
• 959932-22-0 C₁₉H₁₉N₃O₄S 
• 959932-00-4 C₁₆H₁₃N₃O₄S 
• 1123738-15-7 3-bromo-5-hydroxyquinoline 
• 1123738-16-8 C₁₆H₁₁BrN₂O₃ 
• 1123738-17-9 5-(3-nitrobenzyloxy)-3-(4-methylpiperazin-1-yl)quinoline 
• 1268264-05-6 5-(3-fluorobenzyloxy)-3-(4-methylpiperazin-1-yl)quinoline 
• 1268264-06-7 5-(3-cyanobenzyloxy)-3-(4-methylpiperazin-1-yl)quinoline 
• 1268264-32-9 3-(4-methylpiperazin-1-yl)quinolin-5-yl 1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylate 
• 1268264-31-8 3-(4-methylpiperazin-1-yl)quinolin-5-yl 3-nitrobenzoate 
• 1268264-33-0 3-(4-methylpiperazin-1-yl)quinolin-5-yl 3-nitrobenzenesulfonate 
• 1268264-08-9 3-(4-methylpiperazin-1-yl)-N-(3-nitrobenzyl)quinolin-5-amine 
• 1268264-09-0 3-(4-acetylpiperazin-1-yl)-N-(3-nitrobenzyl)quinolin-5-amine 

Relevant articles and documents

Protonmotive force: Development of electrostatic drivers for synthetic molecular motors

Ferrocene has been investigated as a platform for developing protonmotive electrostatic drivers for molecular motors. When two 3-pyridine groups are substituted to the (rapidly rotating) cyclopentadienyl (Cp) rings of ferrocene, one on each Cp, it is shown that the (Cp) eclipsed, π-stacked rotameric conformation is preferred both in solution and in the solid state. Upon quaternization of both of the pyridines substituents, either by protonation or by alkylation, it is shown that the preferred rotameric conformation is one where the pyridinium groups are rotated away from the fully π-stacked conformation. Electrostatic calculations indicate that the rotation is caused by the electrostatic repulsion between the charges. Consistently, when the π-stacking energy is increased π-stacked population increases, and conversely when the electrostatic repulsion is increased π-stacked population is decreased. This work serves to provide an approximate estimate of the amount of torque that the electrostatically driven ferrocene platform can generate when incorporated into a molecular motor. The overall conclusion is that the electrostatic interaction energy between dicationic ferrocene dipyridyl systems is similar to the π-stacking interaction energy and, consequently, at least tricationic systems are required to fully uncouple the π-stacked pyridine substituents.

Tetraazaarenes by the ceramidonine approach

The synthesis of extended heteroarenes via the acid-promoted dehydrocyclisation of arylamino-anthraquinones is examined as an approach to highly conjugated electron-acceptor materials and eventually to heterographene nanoribbons. Whilst the latter perspective is found to remain challenging, the former is exemplified by the synthesis of extended tetraazaheterocycles bearing solubilising alkyl substituents. The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2012.

Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase

A series of quinoxaline inhibitors of c-Met kinase is described. The postulated binding mode was confirmed by an X-ray crystal structure and optimisation of the series was performed on the basis of this structure. Future directions for development of the