116632-57-6

Basic information

• Product Name: 3-Bromoquinolin-5-amine
• Synonyms: 3-Bromoquinolin-5-amine;3-BroMo-5aMinoquinoline;3-Bromo-quinolin-5-ylamine;3-Bromo-5-quinolinamine
• CAS NO: 116632-57-6
• Molecular Formula: C₉H₇BrN₂
• Molecular Weight: 223.06928
• Mol File: 116632-57-6.mol

Chemical Properties

• Boiling Point: 352.5±27.0 °C(Predicted)
• Appearance: /
• Density: 1.649±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 3.09±0.23(Predicted)
• CAS DataBase Reference: 3-Bromoquinolin-5-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromoquinolin-5-amine(116632-57-6)
• EPA Substance Registry System: 3-Bromoquinolin-5-amine(116632-57-6)

Safety Data

• Hazardous Substances Data: 116632-57-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
3-Bromoquinolin-5-amine is used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals for its ability to be incorporated into the molecular structures of these products, enhancing their therapeutic or pesticidal properties.
Used in Drug Development:
3-Bromoquinolin-5-amine is utilized as a starting material in the development of new drugs, where its chemical reactivity allows for the creation of novel molecular entities with potential therapeutic benefits.
Used in Chemical Intermediates Production:
As a chemical intermediate, 3-Bromoquinolin-5-amine is used in the production of various specialty chemicals, contributing to the synthesis of a wide range of compounds with specific applications.
Used in Fluorescent Dyes Production:
3-Bromoquinolin-5-amine is used as a building block for the production of fluorescent dyes, taking advantage of its inherent properties to create dyes with specific spectral characteristics for use in research and industry.
Used in Corrosion Inhibitors Production:
In the field of material protection, 3-Bromoquinolin-5-amine is used in the development of corrosion inhibitors, where its chemical structure provides a means to protect metals from degradation in various environments.
Organic Chemistry Research:
3-Bromoquinolin-5-amine is a valuable tool for organic chemists and researchers, who use its unique reactivity to explore new reaction pathways and develop innovative synthetic methods.

Upstream product

• 607-34-1 5-nitroquinoline 
• 7647-01-0 hydrogenchloride 
• 116632-33-8 3-bromo-5-nitroquinoline 

Downstream Products

• 1123738-15-7 3-bromo-5-hydroxyquinoline 
• 1123738-16-8 C₁₆H₁₁BrN₂O₃ 
• 1123738-17-9 5-(3-nitrobenzyloxy)-3-(4-methylpiperazin-1-yl)quinoline 
• 1416440-62-4 3-bromo-5-chloroquinoline 
• 101861-59-0 3,5-dibromoquinoline 

Relevant articles and documents

Palladium-Catalyzed Carbonylation of (Hetero)Aryl, Alkenyl and Allyl Halides by Means of N-Hydroxysuccinimidyl Formate as CO Surrogate

An efficient Pd-catalyzed carbonylation protocol is described for the coupling of a large panel of aryl, heteroaryl, benzyl, vinyl and allyl halides 2 with the unusual N-hydroxysuccinimidyl (NHS) formate 1 as a CO surrogate to afford the corresponding valuable NHS esters 3. High conversion to the coupling products was achieved with up to 98% yield by means of Pd(OAc)2/Xantphos catalyst system.

Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase

A series of quinoxaline inhibitors of c-Met kinase is described. The postulated binding mode was confirmed by an X-ray crystal structure and optimisation of the series was performed on the basis of this structure. Future directions for development of the