116632-42-9

Basic information

• Product Name: 3-CHLORO-4-IODOTOLUENE
• Synonyms: 3-CHLORO-4-IODOTOLUENE;3-CHLORO-4-IODOTOLUENE 99%;3-Chloro-6-iodotoluene;2-Chloro-1-iodo-4-methylbenzene
• CAS NO: 116632-42-9
• Molecular Formula: C₇H₆ClI
• Molecular Weight: 252.48
• Product Categories: Halogen toluene;Chlorine Compounds;Iodine Compounds
• Mol File: 116632-42-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 140 °C
• Flash Point: 105℃
• Appearance: /
• Density: 1,82 g/cm3
• Vapor Pressure: 0.0368mmHg at 25°C
• Refractive Index: 1.616
• CAS DataBase Reference: 3-CHLORO-4-IODOTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-4-IODOTOLUENE(116632-42-9)
• EPA Substance Registry System: 3-CHLORO-4-IODOTOLUENE(116632-42-9)

Safety Data

• Hazard Codes: Xi,N
• Statements: 36/37/38-51/53-41-37/38
• Safety Statements: 26-36/37/39-61-39
• HazardClass: IRRITANT
• Hazardous Substances Data: 116632-42-9(Hazardous Substances Data)

Usage

General Description

3-Chloro-4-iodotoluene is a chemical compound with the formula C7H6ClI. It is a member of the toluene family, which consists of a benzene ring with a methyl group and both chlorine and iodine atoms attached at different positions. The compound is commonly used as a building block in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure and reactivity make it a valuable intermediate in the synthesis of complex organic molecules. However, 3-chloro-4-iodotoluene is also potentially hazardous, with the potential for causing irritation to the skin, eyes, and respiratory system, as well as being harmful if ingested or inhaled. Therefore, proper handling and precautions must be taken when working with this chemical.

InChI:InChI=1/C7H6ClI/c1-5-2-3-7(9)6(8)4-5/h2-4H,1H3

Upstream product

• 108-41-8 1-chloro-3-methylbenzene 
• 615-65-6 2-chloro-4-methyl-benzenamine 

Downstream Products

• 90649-68-6 1-(2-chloro-4-methylphenyl)ethan-1-one 
• 1293343-79-9 4-[2-(2-chloro-4-methylphenylsulfanyl)phenyl]piperazine-1-carboxylic acid tert-butyl ester 
• 1293343-10-8 1-[2-(2-chloro-4-methylphenylsulfanyl)phenyl]piperazine hydrochloride 
• 1293343-42-6 1-(2-bromophenylsulfanyl)-2-chloro-4-methylbenzene 
• 863977-41-7 [(2-chloro-4-methyl-phenyl)-difluoro-methyl]-phosphonic acid diethyl ester 
• 1143573-50-5 C₁₂H₁₂ClN 
• 142068-83-5 4,4'-bis<3,3',4,4'-tetramethyl-5,5'-bis(ethoxycarbonyl)-2,2'-dipyrrylmethyl>-2-chloro-1,1'-biphenyl 
• 142068-84-6 4,4'-bis(3,3',4,4'-tetramethyl-5,5'-dicarboxy-2,2'-dipyrrylmethyl)-2-chloro-1,1'-biphenyl 
• 142068-85-7 4,4'-bis(3,3',4,4'-tetramethyl-2,2'-dipyrrylmethyl)-2-chloro-1,1'-biphenyl 

Relevant articles and documents

TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS

The present invention relates to tricyclic compounds of formula (I) or pharmaceutically acceptable salt thereof as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthama, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases. (I)

Anisotropic organic compounds

STR1 The invention describes liquid crystalline compounds or formula (I), where A, D and G are independently selected from phenyl, thiophene, hydrogenated phenyl, chlorinated phenyl and fluorinated phenyl, B and E are independently selected from a single bond C= C. C C.C00, azoxy and diazo, k and m are independently selected from 1 and 0, such that m+n is 1 or 2, and R1 and R2 are independently selected from R, R0, alkynyl, thioalkyl, hydrogen, CN, NCS and SCN; provided that at least one of R1 and R2 is selected from CN, NCS and SCN and that at least one of A, D and G is phenyl; and excluding where at least one of R1 and R2 is independently selected as CN and one of A, D or G is not thiophene, and where m is 0, A, and D are phenyl, B is a single bond and only one of R1 or R2 is NCS. Also described are compounds suitable for inclusion in a device utilizing pretransitional characteristics of liquid crystalline materials in the isotropic phase, of general formula (II) where J and Y are independently selected from phenyl, thiophene, hydrogenated phenyl, chlorinated phenyl and fluorinated phenyl, X is selected from C= C. C C.COO azoxy and diazo, k is 1 or 0 and R3 and R4 are independently selected from R, RO, alkynyl, thioalkyl, hydrogen, CN, NCS and SCN; provided that at least one of R3 and R4 is selected from CN, NCS and SCN and that at least one of J and Y is phenyl.

Electron transfer in bis-porphyrin donor-acceptor compounds with polyphenylene spacers shows a weak distance dependence

A series of phenylene-bridged bis-porphyrin adducts have been synthesized, containing one, two, or three phenyl bridges. Complete synthetic details are provided. For studies of photochemical electron transfer, mixed metals wre incorporated, with zinc in one porphyrin macrocycle and FeIII (bis-imidazole) in the other macrocycle. When photoexcited, an electron is transferred from Zn to FeIII. The rate of this process drops only slowly with distance: kα exp(βr), with β = 0.4 A?-1. This dependence can be predicted by a simple theory which assumes that the drop does not reflect increased distance, but rather reflects the break in conjugation which occurs at each phenyl juncture due to the biphenyl twist angle of ca. 50°. Inefficient overlap in this angle results in a rate drop of ca. 6-fold per phenyl ring, in good agreement with the observed results.