116632-54-3

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-3-aminoquinoline is used as an intermediate in the synthesis of pharmaceuticals for its potential role in the development of new drugs. Its unique structure allows it to be a versatile building block in medicinal chemistry.
Used in Dye Industry:
In the dye industry, 2-Chloro-3-aminoquinoline is utilized as an intermediate in the production of various dyes, capitalizing on its chemical properties to create a range of colorants for different applications.
Used in Agrochemical Industry:
2-Chloro-3-aminoquinoline serves as an intermediate in the synthesis of agrochemicals, contributing to the development of pesticides and other agricultural products to enhance crop protection and yield.
Used in Organic Chemistry Research:
As a building block in organic chemistry, 2-Chloro-3-aminoquinoline is used in the development of novel organic compounds for a wide array of purposes, including material science and the creation of new chemical entities with specific properties.
Used in Biological Research:
2-Chloro-3-aminoquinoline may possess biological activities that make it a subject of interest for further investigation in medicinal and biological applications, potentially leading to new discoveries in these fields.

Upstream product

• 742698-74-4 tert-butyl (2-chloroquinolin-3-yl)carbamate 
• 1607439-99-5 3-azido-2-chloroquinoline 
• 128676-84-6 (2-chloroquinolin-3-yl)boronic acid 
• 73776-25-7 2-chloro-3-quinolinecarboxylic acid 
• 5873-00-7 3-amino-quinolin-2-ol 

Downstream Products

• 102469-77-2 N²,N³-diphenyl-quinoline-2,3-diyldiamine 
• 71316-38-6 3-amino-quinoline-2-thiol 
• 1620098-27-2 1-methyl-3-(3-{[4-(1H-pyrazol-4-yl)pyrimidin-2-yl]oxy}phenyl)-1H-pyrrolo[3,2-b]quinoline 
• 1620098-28-3 3-(3-{[4-(4-fluorophenyl)pyrimidin-2-yl]oxy}phenyl)-1-methyl-1H-pyrrolo[3,2-b]quinoline 
• 1620098-29-4 3-(3-{[4-(4-methoxyphenyl)pyrimidin-2-yl]oxy}phenyl)-1-methyl-1H-pyrrolo[3,2-b]quinoline 
• 1620098-30-7 3-[3-(4,5'-bipyrimidin-2-yloxy)phenyl]-1-methyl-1H-pyrrolo[3,2-b]quinoline 
• 1620098-31-8 1-methyl-3-(3-{[4-(morpholin-4-yl)pyrimidin-2-yl]oxy}phenyl)-1H-pyrrolo[3,2-b]quinoline 
• 1620098-32-9 1-methyl-3-(3-{[3-(pyrimidin-5-yl)pyrazin-2-yl]oxy}phenyl)-1H-pyrrolo[3,2-b]quinoline 
• 1620098-16-9 3-(4-{[3-(4-fluorophenyl)pyrazin-2-yl]oxy}phenyl)-1-methyl-1H-pyrrolo[3,2-b]quinoline 
• 1620098-17-0 3-(4-{[3-(4-methoxyphenyl)pyrazin-2-yl]oxy}phenyl)-1-methyl-1H-pyrrolo[3,2-b]quinoline 
• 1620098-18-1 1-methyl-3-(4-{[3-(pyridin-4-yl)pyrazin-2-yl]oxy}phenyl)-1H-pyrrolo[3,2-b]quinoline 
• 1620098-19-2 1-methyl-3-(4-{[3-(pyrimidin-5-yl)pyrazin-2-yl]oxy}phenyl)-1H-pyrrolo[3,2-b]quinoline 
• 1620098-20-5 3-[4-(4,5'-bipyrimidin-2-yloxy)phenyl]-1-methyl-1H-pyrrolo[3,2-b]quinoline 
• 1620098-25-0 1-methyl-3-[3-(tetrahydro-2H-pyran-2-yloxy)phenyl]-1H-pyrrolo[3,2-b]quinoline 

Relevant academic research and scientific papers

Structure-based design of novel human toll-like receptor 8 agonists

Toll-like receptor (TLR)-8 agonists activate adaptive immune responses by inducing robust production of T helper 1-polarizing cytokines, suggesting that TLR8-active compounds might be promising candidate vaccine adjuvants. Recently, a C2-butyl furo[2,3-c]

TOLL-LIKE RECEPTOR 8 AGONISTS

Compounds described herein can be used for therapeutic purposes. The compounds can be TLR agonists, such as TLR8 agonists. The compounds can be included in pharmaceutical compositions and used for therapies were being a TLR8 agonist is useful. The pharmac

Design, synthesis and pharmacological evaluation of novel polycyclic heteroarene ethers as PDE10A inhibitors: Part II

We report the design and synthesis of novel pyrrolo[3,2-b]quinoline containing heteroarene ethers as PDE10A inhibitors with good to excellent potency, selectivity and metabolic stability. Further optimization of this primary series resulted in the identif

QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR

This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to quinoline-derived amides that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.