1166820-32-1

Basic information

• Product Name: 6-{4-[4-(2-bromoethoxy)phenyl]piperidin-1-yl}-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine
• Synonyms: 6-{4-[4-(2-bromoethoxy)phenyl]piperidin-1-yl}-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine
• CAS NO: 1166820-32-1
• Molecular Weight: 470.292
• Mol File: 1166820-32-1.mol

Chemical Properties

• CAS DataBase Reference: 6-{4-[4-(2-bromoethoxy)phenyl]piperidin-1-yl}-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-{4-[4-(2-bromoethoxy)phenyl]piperidin-1-yl}-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine(1166820-32-1)
• EPA Substance Registry System: 6-{4-[4-(2-bromoethoxy)phenyl]piperidin-1-yl}-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine(1166820-32-1)

Safety Data

• Hazardous Substances Data: 1166820-32-1(Hazardous Substances Data)

Upstream product

• 286961-24-8 benzyl 1,2,3,6-tetrahydro-4-(trifluoromethylsulphonyloxy)-pyridine-1-carboxylate 
• 1166820-03-6 benzyl 4-(4-hydroxyphenyl)-5,6-dihydropyridine-1(2H)-carboxylate 
• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 
• 1240300-07-5 2-(4-(1-(3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)-phenoxy)ethylmethanesulfonate 

Downstream Products

• 1255339-74-2 1-ethyl-4-[2-(4-{1-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl}phenoxy)ethyl]piperazin-2-one 

Relevant articles and documents

[1,2,4] TRIAZOLO [4,3-B] PYRIDAZINES AS LIGANDS OF THE ANDROGEN RECEPTOR

The invention concerns bicyclic compounds of Formula (I): wherein, R1, R2, R3, R4, R5, X1, X2, Y, k, m, n and p are as defined in the description. The present invention also relates to processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the treatment of androgen- receptor associated conditions, particularly prostate cancer.