116686-87-4

Basic information

• Product Name: 1-(4-AMINO-3-CHLORO-PHENYL)-PROPAN-1-ONE
• Synonyms: 1-(4-AMINO-3-CHLORO-PHENYL)-PROPAN-1-ONE
• CAS NO: 116686-87-4
• Molecular Formula: C₉H₁₀ClNO
• Molecular Weight: 183.63
• Mol File: 116686-87-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-AMINO-3-CHLORO-PHENYL)-PROPAN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-AMINO-3-CHLORO-PHENYL)-PROPAN-1-ONE(116686-87-4)
• EPA Substance Registry System: 1-(4-AMINO-3-CHLORO-PHENYL)-PROPAN-1-ONE(116686-87-4)

Safety Data

• Hazardous Substances Data: 116686-87-4(Hazardous Substances Data)

Usage

General Description

1-(4-AMINO-3-CHLORO-PHENYL)-PROPAN-1-ONE, also known as 4-amino-3-chloroacetophenone, is a chemical compound with the molecular formula C9H10ClNO. It is a pale yellow to brownish crystalline powder that is insoluble in water but soluble in organic solvents. 1-(4-AMINO-3-CHLORO-PHENYL)-PROPAN-1-ONE is commonly used in the production of pharmaceuticals, specifically as an intermediate in the synthesis of various drugs. It is also used as a building block in the production of other organic compounds. Additionally, 1-(4-AMINO-3-CHLORO-PHENYL)-PROPAN-1-ONE is known to possess certain biological activities, making it of interest in the field of medicinal chemistry. However, it is important to handle this compound with caution, as it may pose certain health and safety risks if not properly managed.

Upstream product

• 2401-21-0 1,2-Dichloro-3-iodobenzene 
• 70-69-9 1-(4-aminophenyl)-1-propanone 

Downstream Products

• 116686-89-6 1-[3-(2,4-Difluoro-phenoxy)-4-nitro-phenyl]-propan-1-one 
• 116686-90-9 1-[4-Amino-3-(2,4-difluoro-phenoxy)-phenyl]-propan-1-one 
• 116686-88-5 1-(3-chloro-4-nitrophenyl)-1-propanone 

Relevant articles and documents

Alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same

This invention relates to new alkane-sulfonanilide derivatives of the formula: STR1 wherein R1, R2 and R8 are each hydrogen, cyano, halogen, lower alkyl, halo (lower) alkyl, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl or lower alkoxy, R3 is lower alkyl, R4 is acyl, cyano, carboxy, hydroxy(lower)-alkyl, mercapto, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, 5-membered unsaturated heterocyclic group which may have amino, lower alkanoylamino, lower alkylthio or lower alkylsulfonyl, phenylthio which may have nitro or amino, lower alkanoyl(lower)alkenyl or a group of the formula: STR2 wherein R6 is hydrogen, amino or lower alkyl and R7 is hydroxy, lower alkoxy, carboxy(lower)alkoxy, lower alkoxycarbonyl(lower)alkoxy, ureido or thioureido, and R5 is hydrogen, halogen, lower alkyl or lower alkanoyl, and pharmaceutically acceptable salts thereof. More particularly, it relates to alkanesulfonanilide derivatives and pharmaceutically acceptable salts thereof which have antiinflammatory activities and analgesic activities, to processes for the preparation thereof, to a pharmaceutical composition comprising the same and to a method for the treatment of inflammatory disease or pains in human being and animals".