1166916-61-5

Basic information

• Product Name: (S)-2-methoxy-N-[1-(3-methoxyphenyl)ethyl]acetamide
• Synonyms: (S)-2-methoxy-N-[1-(3-methoxyphenyl)ethyl]acetamide
• CAS NO: 1166916-61-5
• Molecular Weight: 223.272
• Mol File: 1166916-61-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-methoxy-N-[1-(3-methoxyphenyl)ethyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-methoxy-N-[1-(3-methoxyphenyl)ethyl]acetamide(1166916-61-5)
• EPA Substance Registry System: (S)-2-methoxy-N-[1-(3-methoxyphenyl)ethyl]acetamide(1166916-61-5)

Safety Data

• Hazardous Substances Data: 1166916-61-5(Hazardous Substances Data)

Upstream product

• 38870-89-2 Methoxyacetyl chloride 
• 50919-07-8 (S)-1-(3-methoxyphenyl)ethylamine 

Relevant articles and documents

Chemoenzymatic synthesis of rivastigmine based on lipase-catalyzed processes

(Chemical Equation Presented) A straightforward chemoenzymatic synthesis of enantiomerically pure rivastigmine has been efficiently carried out under mild reaction conditions, with Candida antarctica lipase B responsible for the stereoselective acetylation of the corresponding (R)-alcohol or amine. An exhaustive enzymatic study has been developed exploring the possibilities of carry out enzyme recycling, scaling up the enzymatic process and development of a dynamic kinetic resolution procedure for the production of adequate enantiomerically pure precursors of rivastigmine. Total chemoenzymatic synthesis of this pharmaceutical has been performed in good overall yield from commercially available 3-methoxyacetophenone.