1166994-78-0

Basic information

• Product Name: 11-Dicyclohexylphosphino-12-(2-methoxyphenyl)-9,10-ethenoanthracene dichloromethane adduct, min. 98% o-MeO KITPHOS
• Synonyms: 11-Dicyclohexylphosphino-12-(2-methoxyphenyl)-9,10-ethenoanthracene dichloromethane adduct, min. 98% o-MeO KITPHOS;11-Dicyclohexylphosphino-12-(2-methoxyphenyl)-9,10-ethenoanthracene dichloromethane adduct
• CAS NO: 1166994-78-0
• Molecular Formula: C₃₅H₃₉OP
• Molecular Weight: 506.657321
• Product Categories: organophosphine ligand;Achiral Phosphine;Aryl Phosphine
• Mol File: 1166994-78-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 617.3±55.0 °C(Predicted)
• Appearance: white/Powder
• CAS DataBase Reference: 11-Dicyclohexylphosphino-12-(2-methoxyphenyl)-9,10-ethenoanthracene dichloromethane adduct, min. 98% o-MeO KITPHOS(CAS DataBase Reference)
• NIST Chemistry Reference: 11-Dicyclohexylphosphino-12-(2-methoxyphenyl)-9,10-ethenoanthracene dichloromethane adduct, min. 98% o-MeO KITPHOS(1166994-78-0)
• EPA Substance Registry System: 11-Dicyclohexylphosphino-12-(2-methoxyphenyl)-9,10-ethenoanthracene dichloromethane adduct, min. 98% o-MeO KITPHOS(1166994-78-0)

Safety Data

• Hazardous Substances Data: 1166994-78-0(Hazardous Substances Data)

Usage

Reaction

Useful ligand for the Palladium-catalyzed amination reaction. Useful ligand for Gold(I)-triflimide catalyzed intramolecular cyclizations.

Upstream product

• 1166994-75-7 11-(dicyclohexylphosphinoyl)-12-(2-methoxyphenyl)-9,10-dihydro-9,10-ethenoanthracene 

Downstream Products

• 1188507-63-2 [(11-(dicyclohexylphosphino)-12-(2-methoxyphenyl)-9,10-dihydro-9,10-ethenoanthracene)AuCl] 

Relevant articles and documents

Electron-rich, bicyclic biaryl-like KITPHOS monophosphines via [4+2] cycloaddition between 1-alkynylphosphine oxides and anthracene: Highly efficient ligands for palladium-catalysed C-N and C-C bond formation

Electron-rich, bicyclic biaryl-like KITPHOS monophosphines have been prepared via Diels-Alder cycloaddition between 1-alkynylphosphine oxides and anthracene in an operationally straightforward and highly modular synthetic protocol that will allow access to an architecturally and electronically diverse family of ligands. Palladium complexes of these ligands are highly efficient catalysts for the Buchwald-Hartwig amination and Suzuki-Miyaura coupling of a wide range of aryl chlorides, which for the vast majority of substrate combinations outperform their o-(dicyclohexylphosphino) biphenyl-based counterparts.