116700-44-8

Basic information

• Product Name: Isoquinoline-5-sulfonic acid [2-(N',N''-diphenyl-guanidino)-ethyl]-amide; hydrochloride
• Synonyms: Isoquinoline-5-sulfonic acid [2-(N',N''-diphenyl-guanidino)-ethyl]-amide; hydrochloride
• CAS NO: 116700-44-8
• Molecular Weight: 482.006
• Mol File: 116700-44-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Isoquinoline-5-sulfonic acid [2-(N',N''-diphenyl-guanidino)-ethyl]-amide; hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Isoquinoline-5-sulfonic acid [2-(N',N''-diphenyl-guanidino)-ethyl]-amide; hydrochloride(116700-44-8)
• EPA Substance Registry System: Isoquinoline-5-sulfonic acid [2-(N',N''-diphenyl-guanidino)-ethyl]-amide; hydrochloride(116700-44-8)

Safety Data

• Hazardous Substances Data: 116700-44-8(Hazardous Substances Data)

Upstream product

• 84468-15-5 5-isoquinolinesulfonyl chloride 
• 116700-36-8 H-9 
• 5416-30-8 N,N'-diphenyl-S-methyl isothiourea 

Relevant articles and documents

5-Isoquinolinesulfonamide derivatives. 1. Synthesis and vasodilatory activity of N-(2-guanidinoethyl)-5-isoquinolinesulfonamide derivatives

Two novel series of N-(2-guanidinoalkyl)-5-isoquinolinesulfonamides, 2 and 3, were prepared. Many of the compounds possessed vasodilatory activity when injected locally into the femoral artery of dogs. The most potent compound, 1-amidino-4-(5-isoquinolylsulfonyl)-1,4-perhydrodiazepine, 33, was comparable to diltiazem, which is used clinically as a vasodilator.