116705-69-2

Basic information

• Product Name: threo-(4S,5S)-4-(hydroxymethyl)-2,2-dimethyl-5-(4-nitrophenyl)-1,3-oxazolidine
• CAS NO: 116705-69-2
• Molecular Weight: 252.27
• Mol File: 116705-69-2.mol

Chemical Properties

• CAS DataBase Reference: threo-(4S,5S)-4-(hydroxymethyl)-2,2-dimethyl-5-(4-nitrophenyl)-1,3-oxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: threo-(4S,5S)-4-(hydroxymethyl)-2,2-dimethyl-5-(4-nitrophenyl)-1,3-oxazolidine(116705-69-2)
• EPA Substance Registry System: threo-(4S,5S)-4-(hydroxymethyl)-2,2-dimethyl-5-(4-nitrophenyl)-1,3-oxazolidine(116705-69-2)

Safety Data

• Hazardous Substances Data: 116705-69-2(Hazardous Substances Data)

Upstream product

• 119-62-0 (1S,2S)-2-amino-1-(4-nitrophenyl)propane-1,3-diol 
• 67-64-1 acetone 

Relevant articles and documents

A highly efficient chemoselective cyclocondensation of threo-(1S,2S)-2-amino-1-(4-nitrophenyl)-1,3-propanediol with ketones and isomerization of the condensates

A convenient procedure for highly efficient chemoselective cyclization of threo-(1S.2S)-2-amino-1-(4-nitrophenyl)propane-1,3-diol with some ketones was described. The structures of the condensates were elucidated on the basis of the IR, 1H- and

Regioselectivity of the interaction of (1s,2s)-2-amino-1-(4-nitrophenyl)-1, 3-propanediol with some symmetrical ketones

The interaction of (1S,2S)-2-amino-1-(4-nitrophenyl)-1,3-propanediol with a series of symmetrical ketones has been studied. As a result isomeric oxazolidines are formed in a ratio of 85:15. These oxazolidines were shown to decompose readily under the action of hydrazine.

Resolution of the Enantiomers of (S,R)-1,1'-Bi-2,2'-naphthylhydrogenphosphate by (1R,2R)- and (1S,2S)-2-Amino-1-(4-nitrophenyl)-propane-1,3-diol

The resolution of the diastereoisomeric salts of the title compounds was possible in the presence of a ketone, especially acetone, which forms oxazolidines (3a-d) with the chiral bases.These oxazolidines afforded separable salts with the (S,R)-1,1'-Bi-2,2'-naphthylhydrogenphosphate (4).The structures of these salts were proved by m.s. and n.m.r. spectroscopy.