1167414-90-5

Basic information

• Product Name: (R)-1-(3-CHLOROPHENYL)ETHANAMINE-HCl
• Synonyms: (R)-1-(3-CHLOROPHENYL)ETHANAMINE-HCl;(R)-1-(3-Chlorophenyl)ethanaMine hydrochloride;[(1R)-1-(3-chlorophenyl)ethyl]amine hydrochloride;R-3-chloro-α-methylbenzylamine hydrochloride
• CAS NO: 1167414-90-5
• Molecular Formula: C₈H₁₀ClN*ClH
• Molecular Weight: 192.08564
• Mol File: 1167414-90-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: (R)-1-(3-CHLOROPHENYL)ETHANAMINE-HCl(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(3-CHLOROPHENYL)ETHANAMINE-HCl(1167414-90-5)
• EPA Substance Registry System: (R)-1-(3-CHLOROPHENYL)ETHANAMINE-HCl(1167414-90-5)

Safety Data

• Hazardous Substances Data: 1167414-90-5(Hazardous Substances Data)

Usage

General Description

"(R)-1-(3-Chlorophenyl)ethanamine Hydrochloride", also known as "(R)-3-Chlorophenethylamine Hydrochloride", is a chemical compound consisting of a chiral carbon attached to an amine, an ethyl chain, and 3-chlorophenyl group, further compounded with hydrochloride. The presence of a chlorine atom in the phenyl ring makes it a halogenated aromatic compound, and the (R) connotation indicates that it is a single enantiomer, referring to its specific spatial arrangement. As a chemical, it is typically used in laboratory research and is generally not meant for consumption, with its toxicological properties still largely unknown. It's precise uses in the scientific and manufacturing sectors may vary based on its specific reactivity, stability, and structural characteristics.

Upstream product

• 1164111-46-9 C₈H₈ClN*ClH 

Downstream Products

• 1379647-55-8 (4-{(1R,3S)-3-[(1R)-1-(3-chloro-phenyl)-ethylamino]-cyclopentyl}-phenyl)-acetic acid ethyl ester 

Relevant articles and documents

Rhodium-catalyzed asymmetric hydrogenation of unprotected NH imines assisted by a thiourea

Asymmetric hydrogenation of unprotected NH imines catalyzed by rhodium/bis(phosphine)-thiourea provided chiral amines with up to 97% yield and 95% ee. 1HNMR studies, coupled with control experiments, implied that catalytic chloride-bound intermediates were involved in the mechanism through a dual hydrogen-bonding interaction. Deuteration experiments proved that the hydrogenation proceeded through a pathway consistent with an imine.

NOVEL URACIL COMPOUND HAVING INHIBITORY ACTIVITY ON HUMAN DEOXYURIDINE TRIPHOSPHATASE OR SALT THEREOF

Provided is a uracil compound or a salt thereof, which has potent human dUTPase inhibitory activity and is useful as, for example, an antitumor drug. A uracil compound represented by the general formula (I) or a salt thereof: wherein n represents an integer of 1 to 3; X represents a bond, an oxygen atom, a sulfur atom, or the like; Y represents a linear or branched alkylene group having 1 to 8 carbon atoms, or the like; and Z represents -SO2NR1R2 or -NR3SO2-R4, wherein R1 and R2 each represent an alkyl group having 1 to 6 carbon atoms, an aralkyl group which is optionally substituted, or the like; R3 represents an alkyl group having 1 to 6 carbon atoms, or the like; and R4 represents an aromatic hydrocarbon group, an unsaturated heterocyclic group, or the like.