116750-27-7Relevant academic research and scientific papers
PHOTOACTIVABLE FLUOROPHORENES. 2. SYNTHESIS AND PHOTOACTIVATION OF FUNCTIONALIZED 3-AROYL-2-(2-FURYL)-CHROMONES
Cummings, Richard T.,DiZio, James P.,Krafft, Grant A.
, p. 69 - 72 (2007/10/02)
The synthesis and photochemistry of functionalized 3-aroyl-2-(2-furyl)-chromones 1 which are photoactivable fluorophores are described.Irradiation converts the non-fluorescent furyl chromones to highly fluorescent 1-arylfuro chromones 3.Functionality has been incorporated to permit covalent attachment, impart aqueous solubility and to maximize the fluorescence of the ultimate 1-arylfurochromone fluorophore.An efficient synthetic pathway to the furyl chromones via an intramolecular Dieckman cyclization also is described.
