116782-41-3

Usage

General Description

1,3-Butanediol, 2-methyl-, (2S,3S)- is a chiral chemical compound with the chemical formula C5H12O2. It is also known as (S,S)-2-methyl-1,3-butanediol. This chemical is commonly used in the production of pharmaceuticals, fragrances, and cosmetics. It is a colorless liquid with a slightly sweet taste and a mild, pleasant odor. It is considered to be relatively safe for use and is not known to cause any significant health hazards when handled and used properly. In addition to its industrial applications, this chemical also has some potential therapeutic uses, particularly as a potential treatment for various nervous system disorders.

Upstream product

• 709027-84-9 diethyl (2S,3R)-3-methyl-O-(p-toluenesulfonyloxy)malate 
• 125664-99-5 N-<(2R,3S)-3-hydroxy-2-methylbutanoyl>bornane-10,2-sultam 

Downstream Products

• 1208258-23-4 C₂₄H₂₆O₂ 
• 67253-77-4 (2S,3S,7S)-3,7-dimethylpentadecan-2-yl propionate 
• 92935-19-8 (2S,3S)-2-methyl-3-(3,4,5,6-tetrahydro-2H-pyran-2-yloxy)butyl 4-methylbenzenesulfonate 
• 780772-64-7 tert-Butyl-dimethyl-{(4E,8E)-(2R,6R,10S,11S)-2,6,10-trimethyl-11-[4-(4,4,5,5,6,6,7,7,7-nonafluoro-heptyloxy)-benzyloxy]-dodeca-4,8-dienyloxy}-silane 
• 780772-60-3 tert-Butyl-dimethyl-{(4E,8E)-(2S,6R,10S,11S)-2,6,10-trimethyl-11-[4-(4,4,5,5,6,6,7,7,7-nonafluoro-heptyloxy)-benzyloxy]-dodeca-4,8-dienyloxy}-silane 
• 780772-22-7 tert-Butyl-dimethyl-{(4E,8E)-(2R,6S,10S,11S)-2,6,10-trimethyl-11-[4-(4,4,5,5,6,6,7,7,7-nonafluoro-heptyloxy)-benzyloxy]-dodeca-4,8-dienyloxy}-silane 
• 780772-53-4 tert-Butyl-dimethyl-{(4E,8E)-(2S,6S,10S,11S)-2,6,10-trimethyl-11-[4-(4,4,5,5,6,6,7,7,7-nonafluoro-heptyloxy)-benzyloxy]-dodeca-4,8-dienyloxy}-silane 
• 780773-26-4 (1S,2S,6S,10S)-1-(4,4,5,5,6,6,7,7,7-nonafluoroheptyloxy)-4-(1,2,6,10-tetramethyldodecyloxymethyl)benzene 
• 780773-22-0 (1S,2S,6S,10R)-1-(4,4,5,5,6,6,7,7,7-nonafluoroheptyloxy)-4-(1,2,6,10-tetramethyldodecyloxymethyl)benzene 
• 780773-18-4 (1S,2S,6R,10S)-1-(4,4,5,5,6,6,7,7,7-nonafluoroheptyloxy)-4-(1,2,6,10-tetramethyldodecyloxymethyl)benzene 
• 780772-23-8 (1S,2S,6R,10R)-1-(4,4,5,5,6,6,7,7,7-nonafluoroheptyloxy)-4-(1,2,6,10-tetramethyldodecyloxymethyl)benzene 
• 780772-21-6 tert-Butyl-{(E)-(2R,6S,7S)-2,6-dimethyl-7-[4-(4,4,5,5,6,6,7,7,7-nonafluoro-heptyloxy)-benzyloxy]-oct-4-enyloxy}-dimethyl-silane 
• 780772-30-7 tert-Butyl-{(E)-(2S,6S,7S)-2,6-dimethyl-7-[4-(4,4,5,5,6,6,7,7,7-nonafluoro-heptyloxy)-benzyloxy]-oct-4-enyloxy}-dimethyl-silane 
• 780773-04-8 (4E,8E)-(2R,6R,10S,11S)-2,6,10-Trimethyl-11-[4-(4,4,5,5,6,6,7,7,7-nonafluoro-heptyloxy)-benzyloxy]-dodeca-4,8-dien-1-ol 

Relevant academic research and scientific papers

A concise asymmetric synthesis of (2S,3S,7S)-3,7-dimethylpentadecan-2-yl acetate and propionate, the sex pheromones of pine sawflies

(2S,3S,7S)-3,7-Dimethylpentadecan-2-yl acetate (2) and its propionate analogue (3) are the main sex pheromones of all Neodiprion species and Diprion similes, respectively. Starting from (S)-malic acid and employing a highly chemo-, regio-, and stereoselective tandem ester reduction-epoxide formation-reductive epoxide-opening reaction protocol, an efficient total synthesis of (2S,3S,7S)-2 and -3 is reported herein.

Bornanesultam-directed asymmetric synthesis of crystalline, enantiomerically pure syn aldols

N-acylsultams 2 furnish, via aldolization of their enolates 16 with aldehydes, diastereomerically pure, crystalline syn aldols. The absolute configuration of the product is controlled by the choice of the enolate counterion: 16, M = B → 3; 16, M = Li or S