116794-13-9Relevant academic research and scientific papers
A-C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions
Hanson, Alicia M.,Perera, K. L. Iresha Sampathi,Kim, Jaekyoon,Pandey, Rajesh K.,Sweeney, Noreena,Lu, Xingyun,Imhoff, Andrea,Mackinnon, Alexander Craig,Wargolet, Adam J.,Van Hart, Rochelle M.,Frick, Karyn M.,Donaldson, William A.,Sem, Daniel S.
, p. 4720 - 4738 (2018/05/23)
Estrogen receptor-beta (ERβ) is a drug target for memory consolidation in postmenopausal women. Herein is reported a series of potent and selective ERβ agonists (SERBAs) with in vivo efficacy that are A-C estrogens, lacking the B and D estrogen rings. The
SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOALKANE AND (4'-HYDROXYPHENYL)CYCLOALKENE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM FOR ENHANCED MEMORY CONSOLIDATION
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Paragraph 0128; 0129; 0178; 0179, (2018/10/25)
Disclosed are substituted (4'-hydroxylphenyl)cycloalkane compounds and substituted (4'-hydroxylphenyl)cycloalkene compounds and there use as selective agonists of the estrogen receptor beta isoform (ERβ). The disclosed compounds may be formulated as pharm
PROCESSES FOR PRODUCING p-SUBSTITUTED PHENOLS
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, (2008/06/13)
Para-substituted phenols are produced at high yield and high selectivity without generating a large quantity of a metal containing drain, and further, para-substituted cyclohexylphenols in which the substituents at position 1 and position 4 of cyclohexano
