116869-02-4Relevant articles and documents
A base labile protecting group for peptide synthesis: 2,2,-Bis(4'-nitrophenyl)ethan-1-oxycarbonyl urethanes
Ramage,Blake,Florence,Gray,Raphy,Roach
, p. 8001 - 8024 (2007/10/02)
A base labile urethane (Bnpeoc) group derived from 2,2,-bis(4'-nitrophenyl)ethan-1-ol has been developed as an amine protecting group. This protecting group may be cleaved using the reagents DBN, DBU, DBU/HOAc and piperidine. The preparations of N(α)-Bnpeoc amino acids and applications to peptide/glycopeptide synthesis are described.