1169827-75-1Relevant academic research and scientific papers
Stereoselective synthesis of α-glucosides by neighbouring group participation via an intermediate thiophenium ion
Cox, Daniel J.,Fairbanks, Antony J.
experimental part, p. 773 - 780 (2009/09/30)
The use of a 2-O-(thiophen-2-yl)methyl protecting group allows highly stereoselective α-glucosylation of a trichloroacetimidate donor; increased stereoselectivity, presumably arising from the intramolecular formation of a transient intermediate thiophenium ion, correlates with increased bulk of the glycosyl acceptor.
