1169942-85-1Relevant articles and documents
DRUG AND GENE THERAPY TO TREAT HIGH MYOPIA AND OTHER OCULAR DISORDERS WITH ENLARGED EYE GLOBES
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, (2021/12/29)
This invention relates to a treatment of various eye conditions relating to eye enlargement. The conditions can be treated by inhibiting an upstream protein within the said biological pathway or by increasing the expression of a downstream receptor within
Design and synthesis of boron containing potential pan-RAR inverse agonists
Das, Bhaskar C.,Tang, Xiang-Ying,Evans, Todd
scheme or table, p. 1316 - 1318 (2012/04/04)
We designed and successfully synthesized the compounds 5 and 8 as potential pan-RAR (retinoic acid receptor) agonists. These two compounds were designed based on an existing pan-RAR agonist (BMS493). We synthesized compound 5, in which the carboxylic acid
Boronated phosphonium salts containing arylboronic acid, closo-carborane, or nido-carborane: Synthesis, X-ray diffraction, in vitro cytotoxicity, and cellular uptake
Morrison, Daniel E.,Issa, Fatiah,Bhadbhade, Mohan,Groebler, Ludwig,Witting, Paul K.,Kassiou, Michael,Rutledge, Peter J.,Rendina, Louis M.
experimental part, p. 1305 - 1318 (2011/10/02)
The preparation of boronated triaryl and tetraaryl phosphonium salts of the type [PPh3CH2R]Br [R is 4-boronophenyl (1), 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-yl)phenyl (2), 3-boronophenyl (3), 3-(4,4,5,5-tetramethyl-1,3,2-dioxabo