117-74-8

Usage

InChI:InChI=1/C20H18NO4.H2O/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H2/q+1;/p-1

Upstream product

• 29074-38-2 canadine 
• 522-97-4 canadine 

Downstream Products

• 1388193-65-4 Br^(1-)*C₃₃H₃₈BrN₂O₇⁽¹⁺⁾ 
• 1388193-63-2 Br^(1-)*C₃₂H₃₆BrN₂O₇⁽¹⁺⁾ 
• 1388193-61-0 Br^(1-)*C₃₂H₃₆BrN₂O₇⁽¹⁺⁾ 
• 1388193-60-9 Br^(1-)*C₃₁H₃₄BrN₂O₇⁽¹⁺⁾ 
• 1388193-59-6 Br^(1-)*C₃₁H₃₄BrN₂O₇⁽¹⁺⁾ 
• 1388193-57-4 Br^(1-)*C₃₀H₃₂BrN₂O₇⁽¹⁺⁾ 
• 1388193-56-3 Br^(1-)*C₃₃H₃₈ClN₂O₇⁽¹⁺⁾ 
• 1388193-53-0 Br^(1-)*C₃₂H₃₆ClN₂O₇⁽¹⁺⁾ 
• 1388193-51-8 Br^(1-)*C₃₂H₃₆ClN₂O₇⁽¹⁺⁾ 
• 1388193-50-7 Br^(1-)*C₃₁H₃₄ClN₂O₇⁽¹⁺⁾ 
• 1388193-49-4 Br^(1-)*C₃₁H₃₄ClN₂O₇⁽¹⁺⁾ 
• 1388193-47-2 Br^(1-)*C₃₀H₃₂ClN₂O₇⁽¹⁺⁾ 
• 73777-77-2 polyberbine 

Relevant academic research and scientific papers

PURIFICATION AND CHARACTEIZATION OF (S)-TETRAHYDROBERBERINE OXIDASE FROM CULTURED COPTIS JAPONICA CELLS

(S)-Tetrahydroberberine (THB) oxidase was purified to homogeniety from cultured Coptis japonica cells by DEAE-Sepharose chromatography, gel filration, and HPLC.The enzyme catalysed the removal of four hydrogen atoms from one mol of (S)-THB and produced two mol of hydrogen peroxide and one mol of berberine in the presence of molecular oxygen.The purified enzyme had neither the yellow fluoresence characteristic of flavin derivatives nor an absorption spectrum showing the presence of haem.The enzyme had a M, of 58000 and consisted of two identical subunits of 28000 each.Key Word Index: Coptis japonica; Ranunculaceae; cultured cells; berberine; (S)-tetrahydroberberine; (S)-tetrahydroberberine oxidase

Biotransformation of tetrahydroberberine to berberine by enzymes prepared from cultured coptis japonica cells

Crude enzymes were extracted from cultured Coptis japonica cells producing large amounts of berberine. One of the enantiomers of tetrahydroberberine, (S)-(-)-tetrahydroberberine, was dehydrogenated to berberine by the enzyme system.