117012-71-2Relevant academic research and scientific papers
Novel organophosphorus scaffolds of urease inhibitors obtained by substitution of Morita-Baylis-Hillman adducts with phosphorus nucleophiles
Ntatsopoulos, Vassilis,Vassiliou, Stamatia,Macegoniuk, Katarzyna,Berlicki, ?ukasz,Mucha, Artur
, p. 107 - 120 (2017/04/07)
The reactivity of Morita-Baylis-Hillman allyl acetates was employed to introduce phosphorus-containing functionalities to the side chain of the cinnamic acid conjugated system by nucleophilic displacement. The proximity of two acidic groups, the carboxyla
Potential Inhibitors of Phosphoenolpyruvate (PEP) Carboxylase: Phosphonic Acid Substrate Analogues Derived from Stobbe-Type Condensations of Ethyl 3-(Diethoxyphosphinoyl)propanoate
McFadden, Helen G.,Harris, Roger L. N.,Jenkins, Colin L. D.
, p. 1619 - 1629 (2007/10/02)
Phosphonic acid analogues of 2-(dihydroxyphosphinoyloxy)propenoic acid (PEP), the substrate of PEP carboxylase, were prepared and tested as inhibitors of the enzyme.The required triacids were obtained by mild hydrolysis of the partial esters prepared by S
