117023-15-1

Basic information

• Product Name: 1-[4-(3-{4-[2,2-Bis-(4-fluoro-phenyl)-2-hydroxy-ethyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; compound with (E)-but-2-enedioic acid
• CAS NO: 117023-15-1
• Molecular Weight: 639.693
• Mol File: 117023-15-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[4-(3-{4-[2,2-Bis-(4-fluoro-phenyl)-2-hydroxy-ethyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; compound with (E)-but-2-enedioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(3-{4-[2,2-Bis-(4-fluoro-phenyl)-2-hydroxy-ethyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; compound with (E)-but-2-enedioic acid(117023-15-1)
• EPA Substance Registry System: 1-[4-(3-{4-[2,2-Bis-(4-fluoro-phenyl)-2-hydroxy-ethyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; compound with (E)-but-2-enedioic acid(117023-15-1)

Safety Data

• Hazardous Substances Data: 117023-15-1(Hazardous Substances Data)

Upstream product

• 58113-30-7 4-(3-chloropropoxy)-3-methoxyacetophenone 
• 110-17-8 (2E)-but-2-enedioic acid 
• 107071-83-0 α,α-bis(4-fluorophenyl)-4-piperidineethanol 
• 345-92-6 4,4'-Difluorobenzophenone 
• 498-02-2 1-(3-methoxy-4-hydroxyphenyl)ethanone 
• 107071-84-1 alpha,alpha-bis(4-fluorophenyl)-4-pyridineethanol 
• 108-89-4 picoline 

Relevant articles and documents

Synthesis and Antiallergy Activity of 4-(Diarylhydroxymethyl)-1-piperidines and Structurally Related Compounds

A series of 4-(diarylhydroxymethyl)-1-piperidines was synthesized and evaluated for antiallergy activity.Several analogues had potent activity in the passive foot anaphylaxis (PFA) assay, an IgE-mediated model useful in the detection of compounds possessing antiallergic activity.In particular 1--1-piperidinyl>propoxy>-3-methoxyphenyl>ethanone (1, AHR-5333) was more potent than oxatomide and terfenadine in this assay.