117111-05-4Relevant academic research and scientific papers
Hetero-Diels-Alder reactions of novel 3-triazolyl-nitrosoalkenes as an approach to functionalized 1,2,3-triazoles with antibacterial profile
Lopes, Susana M.M.,Novais, Juliana S.,Costa, Dora C.S.,Castro, Helena C.,Figueiredo, Agnes Marie S.,Ferreira, Vitor F.,Pinho e Melo, Teresa M.V.D.,da Silva, Fernando de Carvalho
, p. 1010 - 1020 (2017/12/15)
The generation and reactivity of 3-triazolyl-nitrosoalkenes are reported for the first time. The study showed that hetero-Diels-Alder reaction of these heterodienes is an interesting synthetic strategy to functionalized 1,2,3-triazoles, including 1,2,3-tr
Intermolecular Thermal Reaction of Arylnitrenes with Furans
Benati, Luisa,Montevecchi, Pier Carlo,Toselli, Maurizio,Spagnolo, Piero
, p. 1859 - 1864 (2007/10/02)
4-Methoxy-, 4-chloro-, and 4-nitro-phenylnitrenes have been thermally generated by decomposition of the corresponding aryl azides in the presence of furan and a series of 2-substituted and 2,5-disubstituted furans. 4-Nitrophenylnitrene has been shown to be capable of undergoing electrophilic addition to the furan ring both at the α- and β-position, whereas only evidence of α-attack has been provided by 4-chlorophenylnitrene.On the other hand, no evidence of electrophilic attack has been obtained with 4-methoxyphenylnitrene, which affords only products ascribable to the triplet nitrene.The formation of a number of products ultimately resulting from nitrene attack at the α-position of the furan ring followed by a ring-opening process and the general occurrence of 1-(4-nitrophenyl)- and 1-(4-chlorophenyl)-1,2,3-triazole from thermolysis of 4-nitro- or 4-chloro-phenyl azide in the presence of the furans examined is discussed.
