117139-98-7

Basic information

• Product Name: N^α-tert-butyloxycarbonyl-N^ε-benzyloxycarbonyllysyl-alanyl-leucine methyl ester
• Synonyms: N^α-tert-butyloxycarbonyl-N^ε-benzyloxycarbonyllysyl-alanyl-leucine methyl ester
• CAS NO: 117139-98-7
• Molecular Weight: 578.706
• Mol File: 117139-98-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N^α-tert-butyloxycarbonyl-N^ε-benzyloxycarbonyllysyl-alanyl-leucine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N^α-tert-butyloxycarbonyl-N^ε-benzyloxycarbonyllysyl-alanyl-leucine methyl ester(117139-98-7)
• EPA Substance Registry System: N^α-tert-butyloxycarbonyl-N^ε-benzyloxycarbonyllysyl-alanyl-leucine methyl ester(117139-98-7)

Safety Data

• Hazardous Substances Data: 117139-98-7(Hazardous Substances Data)

Upstream product

• 7517-19-3 methyl (L)-leucinate hydrochloride 
• 16948-04-2 N^α-tert-butyloxycarbonyl-N^ε-benzyloxycarbonyllysine dicyclohexylammonium salt 
• 7675-46-9 2-nitrophenylsulphenyl-L-alanine dicyclohexylammonium salt 

Downstream Products

• 117170-12-4 (S)-2-[(S)-2-((S)-2-Amino-6-benzyloxycarbonylamino-hexanoylamino)-propionylamino]-4-methyl-pentanoic acid 2,5-dioxo-pyrrolidin-1-yl ester; compound with trifluoro-acetic acid 
• 117169-81-0 (S)-2-[(S)-2-((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-propionylamino]-4-methyl-pentanoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 117140-10-0 (S)-2-[(S)-2-((S)-6-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-hexanoylamino)-propionylamino]-4-methyl-pentanoic acid 

Relevant articles and documents

SERIES OF SEQUENTIAL POLYPEPTIDES CONTAINING LYSINE OR ARGININE: PREPARATION AND CHARACTERIZATION

The sequential polypeptides (Lys-Ala)n, (Lys-Ala-Ala)n, (lys-Ala-Ala-Ala)n, (Lys-Leu-Ala)n, (Lys-Leu-Ala-Ala)n, (Lys-Leu-Ala-Ala-Ala)n, (lys-Ala-Leu)n, (lys-Ala-Leu-Ala)n, (Orn-Leu-Ala)n, (Arg-Ala-Ala)n, (Arg-Leu-Ala)n, (Arg-Leu-Ala-Ala)n, (Arg-Ala-Leu)n, and (Arg-Ala-Leu-Ala)n were synthesized by polymerization of active esters (1-succinimidyl or pentafluorophenyl) of the corresponding Nα-deblocked monomers.The monomers were prepared using the usual methods of peptide synthesis in solution.Upon dialysis, the average molecular weight of the polymers was 6 000-9 000 as determined by sedimentation in ultracentrifuge.Polypeptides, contaning leucine in addition to the basic amino acid, showed a marked tendency to aggregation.CD spectra of the products were measured for characterization.