117147-06-5

Basic information

• Product Name: ethyl 4-hydrazinyl-2-(methylsulfanyl)pyrimidine-5-carboxylate
• Synonyms: ethyl 4-hydrazinyl-2-(methylsulfanyl)pyrimidine-5-carboxylate
• CAS NO: 117147-06-5
• Molecular Weight: 228.275
• Mol File: 117147-06-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 4-hydrazinyl-2-(methylsulfanyl)pyrimidine-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-hydrazinyl-2-(methylsulfanyl)pyrimidine-5-carboxylate(117147-06-5)
• EPA Substance Registry System: ethyl 4-hydrazinyl-2-(methylsulfanyl)pyrimidine-5-carboxylate(117147-06-5)

Safety Data

• Hazardous Substances Data: 117147-06-5(Hazardous Substances Data)

Upstream product

• 53554-29-3 ethyl 4-hydroxy-2-(methylthio)pyrimidine-5-carboxylate 

Downstream Products

• 1306829-95-7 3-bromo-6-(methylsulfanyl)-1H-pyrazolo[3,4-d]pyrimidine 
• 100047-42-5 6-(methylsulfanyl)-1H,2H,3H-pyrazolo[3,4-d]pyrimidin-3-one 

Relevant articles and documents

Novel inhibitors of AP-1 and NF-κB mediated gene expression: Structure-activity relationship studies of ethyl 4-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)pyrimidine-5-carb oxylate

In an effort to identify novel inhibitors of AP-1 and NF-κB mediated transcriptional activation, several analogues of ethyl 4-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)pyrimidine-5-carb oxylate (1) were synthesized and tested in two in vitro assays. The 2-(2'-thienyl) substituted compound (11) was identified as the most potent in this series. (C) 2000 Elsevier Science Ltd. All rights reserved.